Clinicopathologic parameters | No. of Studies | No. of Participants | Pooled OR (95% CI) | P | Model | Heterogeneity |
---|---|---|---|---|---|---|
Chi2, p-value, I2 (%) | ||||||
Age (≥50/< 50) | 2 | 106 | 1.09 (0.51, 2.35) | 0.82 | Fixed | 0.26, 0.61, 0 |
Age (≥60/< 60) | 4 | 213 | 0.81 (0.45, 1.46) | 0.49 | Fixed | 2.33, 0.51, 0 |
Gender (Male/Female) | 7 | 470 | 1.03 (0.71, 1.50) | 0.88 | Fixed | 2.85, 0.83, 0 |
TNM stage (III-IV/I-II) | 5 | 255 | 4.25 (1.71, 10.56) | 0.002 | Random | 8.67, 0.07, 54 |
LNM (Positive/Negative) | 6 | 334 | 3.92 (1.35, 11.41) | 0.01 | Random | 18.81, 0.002, 73 |
DM (Positive/Negative) | 3 | 285 | 2.45 (1.39, 4.30) | 0.002 | Fixed | 0.01, 0.99, 0 |
Vascular invasion (Positive/Negative) | 2 | 159 | 3.98 (2.05, 7.71) | P < 0.0001 | Fixed | 0.22, 0.64, 0 |