Raised CA19–9 and CEA have prognostic relevance in gallbladder carcinoma

BMC Cancer

Table 6 Univariate and multivariate analysis for factors affecting recurrence

Variables		Recurrence(n)	Univariate		Multivariate
Variables		Recurrence(n)	P value	HR (CI)	P value	HR (CI)
Age	< 50	13	0.054	0.420 (0.174–1.016)
Age	> 50	25	0.054	0.420 (0.174–1.016)
Sex	female	26	0.072	0.379 (0.132–1.089)
Sex	Male	12	0.072	0.379 (0.132–1.089)
CEA	< 4	11	0.040	0.352 (0.130–0.954)	0.906	1.093 (0.253–4.725)
CEA	> 4	19	0.040	0.352 (0.130–0.954)	0.906	1.093 (0.253–4.725)
Ca19.9	< 37	21	0.013	0.293 (0.111–0.770)	0.020	5.803 (1.324–25.440)
Ca19.9	> 37	17	0.013	0.293 (0.111–0.770)	0.020	5.803 (1.324–25.440)
T stage1/2		13	0.001	10.989 (3.861–31.275)	0.412	2.111 (0.354–12.582)
T stage3/4		25	0.001	10.989 (3.861–31.275)	0.412	2.111 (0.354–12.582)
Node Negative		12	0.001	5.667 (2.222–14.451)	0.484	1.874 (0.322–10.904)
Node Positive		26	0.001	5.667 (2.222–14.451)	0.484	1.874 (0.322–10.904)
LVI	No	9	0.541	0.704 (0.228–2.171)
LVI	Yes	19	0.541	0.704 (0.228–2.171)
PNI	No	13	0.012	0.214 (0.064–0.716)	0.804	0.788 (0.120–5.164)
PNI	Yes	15	0.012	0.214 (0.064–0.716)	0.804	0.788 (0.120–5.164)

ISSN: 1471-2407