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Table 7 Probabilistic sensitivity analysis results according to PFS and OS. Amounts are presented in MXN pesos

From: Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR mutations

TKI

Mean total cost

Incremental Cost

Effectiveness

Incremental Effectiveness

ICER

Progression Free Survival (PFS)

 Gefitinib

$161,781.47

8.180

 Erlotinib

$218,411.28

$56,629.81

6.701

−1.48

Dominated

 Afatinib

$347,853.28

$129,442.00

9.457

1.28

$101,363.54

Overall Survival (OS)

 Gefitinib

$157,891.46

27.098

 Erlotinib

$207,416.43

$49,524.98

21.774

−5.32

Dominated

 Afatinib

$347,423.61

$140,007.18

37.095

10.00

$14,004.90