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Table 5 Cost-effectiveness analysis results according to PFS and OS for each treatment group. Amounts are presented in MXN pesos

From: Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR mutations

TKI

Mean total cost

Incremental Cost

Effectiveness

Incremental Effectiveness

ICER

Progression Free Survival (PFS)

 Gefitinib

$161,800

 

8.18

 

Lowest cost

 Erlotinib

$215,700

$53,900

6.7

−1.48

Dominated by gefitinib

 Afatinib

$348,200

$186,400

9.46

1.28

$145,625.00 vs gefitinib

Overall Survival (OS)

 Gefitinib

$161,800

 

27.1

 

Lowest cost

 Erlotinib

$215,700

$53,900

21.7

−5.4

Dominated by gefitinib

 Afatinib

$348,200

$186,400

37.1

10

$18,640.00 vs gefitinib