Table 4 Cost of TKI therapy and cost of related unwanted effects (UE). Amounts are presented in MXN pesos
Afatinib (n = 40) | Erlotinib (n = 26) | Gefitinib (n = 33) | p-value | ||||
|---|---|---|---|---|---|---|---|
Mean (SD) | Median | Mean (SD) | Median | Mean (SD) | Median | ||
TKI cost | |||||||
Daily cost | 722 (130) | 765 | 794 (96) | 819 | 451 (0) | 451 | < 0.001 |
Total cost | 337,325 (299,832) | 238,298 | 200,506 (137,831) | 183,384 | 149,645 (107,139) | 126,299 | < 0.001 |
UE cost | |||||||
Medications | 6846 (21,203) | 2485 | 3479 (5727) | 897 | 2212 (4762) | 98 | < 0.05 |
Consultation | 4373 (5751) | 1732 | 3797 (4382) | 2598 | 4304 (6125) | 1732 | 0.843 |
Total | 11,219 (23,734) | 6948 | 7276 (8498) | 5267 | 6516 (8986) | 2719 | 0.262 |
TOTAL TKI + UE | 348,544 (311,386) | 246,258 | 207,782 (143,566) | 186,685 | 156,161 (111,330) | 126,299 | < 0.001 |