Fig. 7

THRB is expressed independently of other NHRs and refines survival prognostication in endometrial tumors. a The odds ratio (calculated using Fisher’s exact test) is shown for each possible pairwise combination of the 6 NHRs. Large odds ratios (> 1) correspond to a positive interaction between any two pairs of NHRs. Asterisks within cells correspond to statistically significant odds ratios calculated using Fisher’s exact test at the following thresholds: * = q < 0.01, ** = q < 0.001, *** = q < 0.0001. b Left panel: Kaplan-Meier survival analysis between tumor subgroups defined by expression of both ESR1 and PGR (DP, for double-positive) or by the absence of expression of both ESR1 and PGR (DN, for double-negative). b Kaplan-Meier survival analysis of DN tumors subdivided by THRB expression status (either positive or negative for present or absent, respectively). Asterisks representing q-values are as described for panel a