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Table 1 Baseline characteristics of PB patients in different stratifications of histologic subtype

From: Epidemiological features and survival outcomes in patients with malignant pulmonary blastoma: a US population-based analysis

Patient Characteristics

All patients Cases (%)

Histologic Subtype (Cases, %)

CBPB (91, 51.5%)

PPB (56, 31.6%)

WDFA (30, 16.9%)

p value

Age at diagnosis (years)

    

<0.001 ***

  ≤ 14

67(37.9%)

11 (12.1%)

55 (98.2%)

1 (3.3%)

 

 15–64

74 (41.8%)

50 (54.9%)

0 (0.0%)

24 (80.0%)

 

  ≥ 65

36 (20.3%)

30 (33.0%)

1 (1.8%)

5 (16.7%)

 

Sex

    

0.841

 Male

79 (44.6%)

42 (46.2%)

25 (44.6%)

12 (40.0%)

 

 Female

98 (55.4%)

49 (53.8%)

31 (55.4%)

18 (60.0%)

 

Race/Ethnicity

    

0.083

 White

130 (73.4%)

69 (75.8%)

44 (78.6%)

17 (56.7%)

 

 Black

36 (20.3%)

19 (20.9%)

7 (12.5%)

10 (33.3%)

 

 Other

11 (6.2%)

3 (3.3%)

5 (8.9%)

3 (10.0%)

 

Year of diagnosis

    

<0.001 ***

 1988–2006

81 (45.8%)

57 (62.6%)

17 (30.4%)

7 (23.3%)

 

 2007–2016

96 (54.2%)

34 (37.4%)

39 (69.6%)

23 (76.7%)

 

Anatomical Laterality

    

0.418

 Left

75 (42.4%)

35 (38.5%)

29 (51.8%)

11 (36.7%)

 

 Right

98 (55.3%)

53 (58.2%)

26 (46.4%)

19 (63.3%)

 

 Others

4 (2.3%)

3 (3.3%)

1 (1.8%)

0 (0.0%)

 

Primary Site

    

0.085

 Upper lobe

72 (40.7%)

36 (39.6%)

19 (33.9%)

17 (56.7%)

 

 Lower lobe

50 (28.2%)

29 (31.9%)

13 (23.2%)

8 (26.7%)

 

 Other sites

55 (31.3%)

26 (28.6%)

24 (42.9%)

5 (16.7%)

 

Clinical Stage

    

0.495

 Localized

92 (52.0%)

43 (47.3%)

29 (51.8%)

20 (66.7%)

 

 Regional

50 (28.2%)

28 (30.8%)

16 (28.6%)

6 (20.0%)

 

 Distant

35 (19.8%)

20 (22.0%)

11 (19.6%)

4 (13.3%)

 

Surgery

    

0.108

 Yes

153 (86.4%)

74 (81.3%)

51 (91.1%)

28 (93.3%)

 

 No

24 (13.6%)

17 (18.7%)

5 (8.9%)

2 (6.7%)

 

Only Primary

    

0.080

 Yes

137 (77.4%)

67 (73.6%)

49 (87.5%)

21 (70.0%)

 

 No

40 (22.6%)

24 (26.4%)

7 (12.5%)

9 (30.0%)

 

First Primary

    

0.013 *

 Yes

152 (85.9%)

75 (82.4%)

54 (96.4%)

23 (76.7%)

 

 No

25 (14.1%)

16 (17.6%)

2 (3.6%)

7 (23.3%)

 
  1. A total of 177 patients with malignant PB were stratified by different histologic subtype, and the demographic and clinical characteristics were summarized by calculating the frequencies for categorical variables. P value was calculated by the chi-square analysis. All tests were 2-sided, and statistical significance was set as p-value of < 0.05. * and *** indicated p<0.05, p<0.001 respectively (R program, Version 3.6.3, R core team)
  2. PB pulmonary blastoma, PPB pleuropulmonary blastoma, WDFA well-differentiated fetal adenocarcinoma, CBPB classic biphasic PB