DLBCL with amplification of JAK2/PD-L2 exhibits PMBCL-like CNA pattern and worse clinical outcome resembling those with MYD88 L265P mutation

Table 1 The clinicopathological characteristics of 8 DLBCL with JAK2/PD-L2 Amplification and 5 PMBCL

No.	Diagnosis	Site	Sex	Age	IPI _risk	Hans algorithm	MYC_ Break-apart	MYD88_ L265P	*JAK2*_ amp	*PD-L2*_ amp
1	DLBCL	Spleen	Female	49	low	Non_GCB	Normal	–	+	+
2	DLBCL	Cervical lymph node	Male	45	low_intermediate	Non_GCB	Normal	–	+	+
3	DLBCL	Stomach	Female	34	low_intermediate	Non_GCB	Normal	–	+	+
4	DLBCL	Stomach	Male	53	low	Non_GCB	Normal	–	+	–
5	DLBCL	Colon	Male	39	high	GCB	Normal	–	+	–
6	DLBCL	Cervical lymph node	Female	27	high_intermediate	Non_GCB	Normal	–	+	+
7	DLBCL	Nasal cavity	Male	63	high_intermediate	GCB	Break_apart	+	+	+
8	DLBCL	Cervical lymph node	Female	70	low_intermediate	Non_GCB	Normal	–	+	+
9	PMBCL	Cervical lymph node	Male	27	low	NA	Normal	–	+	+
10	PMBCL	Mediastinum	Female	19	low	NA	Normal	–	+	+
11	PMBCL	Mediastinum	Female	36	low	NA	Normal	–	+	+
12	PMBCL	Mediastinum	Female	31	high_intermediate	NA	Normal	–	+	+
13	PMBCL	Mediastinum	Male	22	low	NA	Normal	–	+	+

ISSN: 1471-2407