Skip to main content

Table 3 Hazard ratios (95% CI) for colorectal cancer-specific and all-cause mortality among patients with colorectal cancer by quintile of post-diagnosis EDIH score

From: Post-diagnosis dietary insulinemic potential and survival outcomes among colorectal cancer patients

  Quintiles of the empirical dietary index for hyperinsulinemia (EDIH) score P-trend
Statistical model Quintile 1 Quintile 2 Quintile 3 Quintile 4 Quintile 5
Colorectal cancer-specific mortality
 Deaths/Patients alive 43/300 60/284 56/288 57/287 56/287  
 Minimally-adjusted model 1 (reference) 1.39 (0.94, 20.6) 1.27 (0.85, 1.90) 1.41 (0.94, 2.11) 1.62 (1.08, 2.42) 0.03
 Fully adjusted model 1 (reference) 1.44 (0.96, 2.18) 1.33 (0.87, 2.02) 1.45 (0.94, 2.26) 1.66 (1.03, 2.69) 0.07
All-cause mortality
 Deaths/Patients alive 178/165 204/140 204/140 215/129 207/136  
 Minimally-adjusted model 1 (reference) 1.22 (1.00, 1.49) 1.21 (0.99, 1.48) 1.46 (1.19, 1.78) 1.35 (1.10, 1.65) 0.002
 Fully adjusted model 1 (reference) 1.23 (1.00, 1.52) 1.20 (0.97, 1.49) 1.39 (1.11, 1.73) 1.24 (0.97, 1.58) 0.08
  1. The minimally-adjusted models was adjusted for age at diagnosis, post-diagnosis body mass index, total energy intake, sex, race, year of diagnosis, cancer stage, grade of tumor differentiation, and location of primary tumor within the colon; the fully-adjusted model was additionally adjusted for post-diagnosis physical activity, post-diagnosis pack years of smoking, post-diagnosis regular aspirin use, weight change pre to post-diagnosis, post-diagnosis total alcohol intake, and pre-diagnosis EDIH score