Table 1 Postdiagnosis characteristics of colorectal cancer patients by quintiles of postdiagnosis empirical dietary index for hyperinsulinemia (EDIH) score; n = 1718
From: Post-diagnosis dietary insulinemic potential and survival outcomes among colorectal cancer patients
Characteristic | Total population (n = 1718) | Quintiles of the empirical dietary index for hyperinsulinemia (EDIH) scorea,b | ||||
|---|---|---|---|---|---|---|
Quintile 1 (−4.28 to < −0.71) (n = 344) | Quintile 2 (−0.71 to < − 0.25) (n = 353) | Quintile 3 (− 0.25 to < 0.10) (n = 349) | Quintile 4 (0.10 to < 0.51) (n = 336) | Quintile 5 (0.51 to 4.00) (n = 336) | ||
Female, % | 65.1 | 65.1 | 65.1 | 65.1 | 65.1 | 65.1 |
Age at diagnosisd | 68.3 (9.2) | 68.1 (8.8) | 69.1 (8.8) | 68.9 (8.8) | 67.6 (9.6) | 67.6 (9.8) |
Age at diagnosis by sexd | ||||||
 Female | 67.6 (9.0) | 68.0 (8.7) | 68.3 (8.6) | 68.1 (8.6) | 67.3 (9.5) | 66.0 (9.6) |
 Male | 69.7 (9.3) | 68.4 (9.2) | 70.6 (8.9) | 70.4 (8.9) | 68.2 (9.7) | 70.6 (9.7) |
Current smoker, % | 7.1 | 4.6 | 6.6 | 9.0 | 6.4 | 9.0 |
Pack-years of smoking | 16.3 (22.2) | 16.0 (20.8) | 16.0 (20.5) | 14.1 (22.0) | 17.8 (23.9) | 17.7 (23.4) |
Body mass index, kg/m2 | 26.1 (4.4) | 25.1 (4.0) | 25.6 (4.1) | 25.9 (4.6) | 26.5 (4.5) | 27.3 (4.6) |
Overweight (BMI ≥ 25, < 30), % | 42.5 | 35.7 | 41.5 | 42.7 | 47.4 | 45.0 |
Obese (BMI ≥ 30), % | 16.0 | 10.4 | 13.0 | 14.3 | 18.1 | 25.0 |
Physical activity, MET-h/weekc | 18.5 (22.5) | 21.8 (25.4) | 20.5 (24.3) | 18.1 (23.3) | 18.2 (20.7) | 13.8 (17.7) |
Physical activity, MET-h/weekc,d by sex | ||||||
 Female | 15.1 (19.8) | 17.4 (19.9) | 17.4 (23.5) | 14.1 (20.8) | 14.5 (19.0) | 11.9 (13.5) |
 Male | 25.0 (25.7) | 30.4 (31.3) | 26.2 (24.7) | 25.3 (24.4) | 25.8 (23.1) | 17.1 (22.6) |
Non-alcohol drinkers, % | 40.2 | 24.3 | 38.3 | 39.1 | 46.3 | 53.0 |
Regular aspirin use, % | 30.4 | 30.7 | 30.8 | 31.2 | 26.6 | 33.0 |
Location of cancer in the colon, % | ||||||
 Proximal colon | 43.7 | 45.4 | 45.7 | 41.1 | 43.7 | 42.6 |
 Distal colon | 33.3 | 33.1 | 31.2 | 31.5 | 37.0 | 32.9 |
 Rectum | 22.3 | 21.0 | 22.0 | 26.7 | 17.9 | 24.2 |
 Unspecified | 0.7 | 0.5 | 1.1 | 0.8 | 1.4 | 0.2 |
Stage at diagnosis, % | ||||||
 Stage I | 37.7 | 39.9 | 36.0 | 35.1 | 39.7 | 36.1 |
 Stage II | 33.8 | 32.2 | 35.7 | 35.5 | 31.4 | 34.9 |
 Stage III | 28.5 | 27.9 | 28.3 | 29.3 | 29.0 | 29.0 |
Median survival time, years | 10.8 (7.3) | 11.5 (7.3) | 11.2 (7.7) | 11.0 (7.2) | 10.1 (7.2) | 10.2 (6.9) |
Median survival time by stage,d years | ||||||
 Stage I | 10.7 | 13.0 | 11.6 | 11.7 | 8.6 | 9.9 |
 Stage II | 9.9 | 9.8 | 9.9 | 9.9 | 9.1 | 10.6 |
 Stage III | 8.0 | 9.2 | 8.2 | 8.5 | 10.0 | 6.1 |
Weight change categoriesd, % | ||||||
 Stable weight (−2.5 to 2.5 kg) | 41.6 | 47.5 | 41.0 | 39.5 | 40.4 | 38.4 |
 Gained more than 2.5 kg | 24.7 | 19.8 | 28.9 | 25.1 | 22.4 | 26.6 |
 Lost more than 2.5 kg | 33.7 | 32.7 | 30.1 | 35.4 | 37.2 | 34.9 |