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Table 1 Postdiagnosis characteristics of colorectal cancer patients by quintiles of postdiagnosis empirical dietary index for hyperinsulinemia (EDIH) score; n = 1718

From: Post-diagnosis dietary insulinemic potential and survival outcomes among colorectal cancer patients

Characteristic Total population (n = 1718) Quintiles of the empirical dietary index for hyperinsulinemia (EDIH) scorea,b
Quintile 1
(−4.28 to < −0.71)
(n = 344)
Quintile 2
(−0.71 to < − 0.25)
(n = 353)
Quintile 3
(− 0.25 to < 0.10)
(n = 349)
Quintile 4
(0.10 to < 0.51)
(n = 336)
Quintile 5
(0.51 to 4.00)
(n = 336)
Female, % 65.1 65.1 65.1 65.1 65.1 65.1
Age at diagnosisd 68.3 (9.2) 68.1 (8.8) 69.1 (8.8) 68.9 (8.8) 67.6 (9.6) 67.6 (9.8)
Age at diagnosis by sexd
 Female 67.6 (9.0) 68.0 (8.7) 68.3 (8.6) 68.1 (8.6) 67.3 (9.5) 66.0 (9.6)
 Male 69.7 (9.3) 68.4 (9.2) 70.6 (8.9) 70.4 (8.9) 68.2 (9.7) 70.6 (9.7)
Current smoker, % 7.1 4.6 6.6 9.0 6.4 9.0
Pack-years of smoking 16.3 (22.2) 16.0 (20.8) 16.0 (20.5) 14.1 (22.0) 17.8 (23.9) 17.7 (23.4)
Body mass index, kg/m2 26.1 (4.4) 25.1 (4.0) 25.6 (4.1) 25.9 (4.6) 26.5 (4.5) 27.3 (4.6)
Overweight (BMI ≥ 25, < 30), % 42.5 35.7 41.5 42.7 47.4 45.0
Obese (BMI ≥ 30), % 16.0 10.4 13.0 14.3 18.1 25.0
Physical activity, MET-h/weekc 18.5 (22.5) 21.8 (25.4) 20.5 (24.3) 18.1 (23.3) 18.2 (20.7) 13.8 (17.7)
Physical activity, MET-h/weekc,d by sex
 Female 15.1 (19.8) 17.4 (19.9) 17.4 (23.5) 14.1 (20.8) 14.5 (19.0) 11.9 (13.5)
 Male 25.0 (25.7) 30.4 (31.3) 26.2 (24.7) 25.3 (24.4) 25.8 (23.1) 17.1 (22.6)
Non-alcohol drinkers, % 40.2 24.3 38.3 39.1 46.3 53.0
Regular aspirin use, % 30.4 30.7 30.8 31.2 26.6 33.0
Location of cancer in the colon, %
 Proximal colon 43.7 45.4 45.7 41.1 43.7 42.6
 Distal colon 33.3 33.1 31.2 31.5 37.0 32.9
 Rectum 22.3 21.0 22.0 26.7 17.9 24.2
 Unspecified 0.7 0.5 1.1 0.8 1.4 0.2
Stage at diagnosis, %
 Stage I 37.7 39.9 36.0 35.1 39.7 36.1
 Stage II 33.8 32.2 35.7 35.5 31.4 34.9
 Stage III 28.5 27.9 28.3 29.3 29.0 29.0
Median survival time, years 10.8 (7.3) 11.5 (7.3) 11.2 (7.7) 11.0 (7.2) 10.1 (7.2) 10.2 (6.9)
Median survival time by stage,d years
 Stage I 10.7 13.0 11.6 11.7 8.6 9.9
 Stage II 9.9 9.8 9.9 9.9 9.1 10.6
 Stage III 8.0 9.2 8.2 8.5 10.0 6.1
Weight change categoriesd, %
 Stable weight (−2.5 to 2.5 kg) 41.6 47.5 41.0 39.5 40.4 38.4
 Gained more than 2.5 kg 24.7 19.8 28.9 25.1 22.4 26.6
 Lost more than 2.5 kg 33.7 32.7 30.1 35.4 37.2 34.9
  1. aValues are means (SD) for continuous variables and percentages for categorical variables and are standardized to the age distribution of the study population
  2. bEDIH scores were adjusted for total energy intake
  3. cMetabolic equivalents from recreational and leisure-time activities
  4. dValue is not age adjusted