Table 1 One-, three-, and five-year cumulative incidence of mortality in stage I SCLC patients
Characteristics | N | % | Event | % | Cancer-specific death | Death from other causes | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1-year (%) | 3-year (%) | 5-year (%) | P | 1-year (%) | 3-year (%) | 5-year (%) | P | |||||
Total | 1811 | Â | 1221 | Â | 28.7 | 56.5 | 61.5 | Â | 5.8 | 11.1 | 13.6 | Â |
Age at diagnosis |  |  |  |  |  |  |  | < 0.001 |  |  |  | 0.001 |
  < 60 years | 342 | 18.9 | 192 | 15.7 | 18.6 | 49.8 | 53.1 |  | 5.2 | 7.7 | 8.2 |  |
 60–75 years | 981 | 54.2 | 640 | 52.4 | 26.1 | 53.5 | 59.5 |  | 5.5 | 10.7 | 14.3 |  |
  > 75 years | 488 | 26.9 | 389 | 31.9 | 40.9 | 67.1 | 71.4 |  | 6.9 | 14.2 | 15.9 |  |
Gender | Â | Â | Â | Â | Â | Â | Â | 0.574 | Â | Â | Â | 0.016 |
 Female | 949 | 52.4 | 619 | 50.7 | 27.3 | 56.3 | 60.5 |  | 5.1 | 9.1 | 11.3 |  |
 Male | 862 | 47.6 | 602 | 49.3 | 30.1 | 56.7 | 62.6 |  | 6.5 | 13.3 | 16.0 |  |
Race | Â | Â | Â | Â | Â | Â | Â | 0.690 | Â | Â | Â | 0.183 |
 White | 1578 | 87.1 | 1064 | 87.1 | 28.9 | 56.1 | 60.8 |  | 5.9 | 11.3 | 13.8 |  |
 Black | 167 | 9.2 | 111 | 9.1 | 26.4 | 57.9 | 66.0 |  | 5.7 | 7.8 | 9.9 |  |
 Others | 66 | 3.7 | 46 | 3.8 | 27.7 | 64.3 | 66.6 |  | 3.3 | 15.1 | 17.4 |  |
Anatomic sites |  |  |  |  |  |  |  | < 0.001 |  |  |  | 0.048 |
 Upper | 1025 | 56.6 | 685 | 56.1 | 26.5 | 55.9 | 60.6 |  | 5.6 | 11.8 | 14.5 |  |
 Middle | 115 | 6.4 | 76 | 6.2 | 22.7 | 51.6 | 55.1 |  | 12.5 | 19.8 | 19.8 |  |
 Lower | 505 | 27.9 | 336 | 27.5 | 29.4 | 55.7 | 61.8 |  | 5.1 | 8.0 | 11.1 |  |
 Bronchus/others | 166 | 9.2 | 124 | 10.2 | 43.6 | 66.0 | 70.5 |  | 4.5 | 9.9 | 10.8 |  |
Primary tumor location | Â | Â | Â | Â | Â | Â | Â | 0.221 | Â | Â | Â | 0.682 |
 Left-sided | 793 | 43.8 | 522 | 42.8 | 28.1 | 55.3 | 59.8 |  | 6.2 | 12.0 | 14.1 |  |
 Right-sided | 1018 | 56.2 | 699 | 57.2 | 29.1 | 57.4 | 62.8 |  | 5.5 | 10.4 | 13.1 |  |
Tumor size |  |  |  |  |  |  |  | < 0.001 |  |  |  | 0.030 |
  ≤ 3 cm | 967 | 53.4 | 602 | 49.3 | 23.7 | 50.6 | 55.0 |  | 5.7 | 12.1 | 15.7 |  |
 3–5 cm | 523 | 28.9 | 379 | 31.0 | 30.5 | 59.6 | 66.1 |  | 7.1 | 10.9 | 12.1 |  |
> 5 cm | 321 | 17.7 | 240 | 19.7 | 40.5 | 68.8 | 73.3 |  | 3.9 | 8.5 | 9.5 |  |
Tumor extension |  |  |  |  |  |  |  | < 0.001 |  |  |  | 0.005 |
 Local | 1526 | 84.3 | 1020 | 83.5 | 27.9 | 55.4 | 59.7 |  | 6.3 | 11.8 | 14.6 |  |
 Regional | 285 | 15.7 | 201 | 16.5 | 32.5 | 62.2 | 71.3 |  | 3.3 | 7.3 | 8.0 |  |
Grading | Â | Â | Â | Â | Â | Â | Â | 0.038 | Â | Â | Â | 0.375 |
 Good or moderate | 34 | 1.9 | 18 | 1.5 | 16.3 | 36.6 | 41.3 |  | 3.1 | 6.8 | 16.7 |  |
 Poor | 343 | 18.9 | 207 | 17.0 | 26.3 | 51.3 | 54.1 |  | 4.9 | 11.8 | 13.3 |  |
 Undifferentiated | 439 | 24.2 | 318 | 26.0 | 26.5 | 58.0 | 65.0 |  | 5.6 | 8.4 | 11.6 |  |
 NOS | 995 | 54.9 | 678 | 55.5 | 30.8 | 58.1 | 62.9 |  | 6.3 | 12.3 | 14.5 |  |
Surgery |  |  |  |  |  |  |  | < 0.001 |  |  |  | 0.593 |
 Yes | 457 | 25.2 | 214 | 17.5 | 11.2 | 35.6 | 40.4 |  | 4.6 | 9.5 | 12.0 |  |
 No | 1354 | 74.8 | 1007 | 82.5 | 34.5 | 63.4 | 68.5 |  | 6.2 | 11.6 | 14.1 |  |
Chemotherapy |  |  |  |  |  |  |  | < 0.001 |  |  |  | < 0.001 |
 Yes | 1217 | 67.2 | 783 | 64.1 | 23.8 | 54.0 | 60.0 |  | 3.6 | 8.6 | 11.2 |  |
 No | 594 | 32.8 | 438 | 35.9 | 38.7 | 61.8 | 64.6 |  | 10.4 | 16.3 | 18.6 |  |
Radiotherapy |  |  |  |  |  |  |  | < 0.001 |  |  |  | 0.773 |
 Yes | 929 | 51.3 | 595 | 48.7 | 21.7 | 52.1 | 58.8 |  | 4.1 | 10.3 | 13.3 |  |
 No | 882 | 48.7 | 626 | 51.3 | 36.0 | 61.2 | 64.4 |  | 7.6 | 12.0 | 13.8 |  |