Table 5 Risk factors for indeterminate, biochemical or structural incomplete response at last follow-up visit
Initial model | Final model | ||||||
|---|---|---|---|---|---|---|---|
Variable | Patients at risk, n | OR | 95% CI | p value | OR | 95% CI | p value |
Age, years | |||||||
< 45 | 38 | 1.0 | 1.0 | ||||
≥ 45 | 69 | 5.3 | 2.2–12.8 | <.001 | 3.8 | 1.2–11.9 | 0.02 |
Sex | |||||||
Female | 69 | 1.0 | |||||
Male | 38 | 1.5 | 0.6–3.6 | 0.37 | |||
Initial 2015 ATA risk-stratification | |||||||
LR | 22 | 1.0 | |||||
IR | 66 | 5.7 | 2.0–16.3 | <.01 | |||
HR | 19 | 38.6 | 4.2–349.5 | <.01 | |||
Aggressive histological subtypes | |||||||
No | 82 | 1.0 | |||||
Yes | 25 | 3.0 | 1.0–9.7 | 0.06 | |||
Site of PD | |||||||
LN only | 62 | 1.0 | 1.0 | ||||
DM and/or TB disease with or without LN | 45 | 1.5 | 0.7–3.5 | 0.33 | 6.8 | 1.4–34.0 | 0.02 |
Tumor burden of PD | |||||||
Very small-volume | 24 | 1.0 | 1.0 | ||||
Small-volume (< 10 mm) | 25 | 7.7 | 2.2–27.5 | <.01 | 15.1 | 2.6–89.3 | <.01 |
Large-volume (≥10 mm) | 58 | 16.3 | 5.1–52.4 | <.0001 | 19.2 | 3.8–98.8 | <.001 |
RAI and 18FDG status of PD | |||||||
RAI+/18FDG- or NP | 55 | 1.0 | 1.0 | ||||
RAI−/18FDG- or NP | 7 | 1.4 | 0.3–6.80 | 0.69 | 1.5 | 0.2–11.0 | 0.71 |
RAI- or RAI+/18FDG+ | 45 | 14.5 | 4.0–52.5 | <.0001 | 8.7 | 1.8–41.9 | <.01 |