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Table 5 Risk factors for indeterminate, biochemical or structural incomplete response at last follow-up visit

From: Tumor burden of persistent disease in patients with differentiated thyroid cancer: correlation with postoperative risk-stratification and impact on outcome

   Initial model Final model
Variable Patients at risk, n OR 95% CI p value OR 95% CI p value
Age, years
  < 45 38 1.0    1.0   
  ≥ 45 69 5.3 2.2–12.8 <.001 3.8 1.2–11.9 0.02
Sex
 Female 69 1.0      
 Male 38 1.5 0.6–3.6 0.37    
Initial 2015 ATA risk-stratification
 LR 22 1.0      
 IR 66 5.7 2.0–16.3 <.01    
 HR 19 38.6 4.2–349.5 <.01    
Aggressive histological subtypes
 No 82 1.0      
 Yes 25 3.0 1.0–9.7 0.06    
Site of PD
 LN only 62 1.0    1.0   
 DM and/or TB disease with or without LN 45 1.5 0.7–3.5 0.33 6.8 1.4–34.0 0.02
Tumor burden of PD
 Very small-volume 24 1.0    1.0   
 Small-volume (< 10 mm) 25 7.7 2.2–27.5 <.01 15.1 2.6–89.3 <.01
 Large-volume (≥10 mm) 58 16.3 5.1–52.4 <.0001 19.2 3.8–98.8 <.001
RAI and 18FDG status of PD
 RAI+/18FDG- or NP 55 1.0    1.0   
 RAI−/18FDG- or NP 7 1.4 0.3–6.80 0.69 1.5 0.2–11.0 0.71
 RAI- or RAI+/18FDG+ 45 14.5 4.0–52.5 <.0001 8.7 1.8–41.9 <.01