Table 4 Multivariate analysis of prognostic factors for overall survival (OS) and disease-free survival (DFS) in matched cohort

Age(y)

<0.001

0.172

 ≤ 60

1

1

 >60

4.236

1.915–9.368

1.606

0.813–3.170

ASA

–

0.071

 I

1

 II- III

1.952

0.943–4.040

Location

0.099

0.012

 Mid/high

1

1

 Low

1.801

0.894–3.629

2.305

1.203–4.417

Preoperative CEA (ng/ml)

0.908

–

 ≤ 5

1

 >5

0.954

0.431–2.110

Preoperative CA19–9 (U/ml)

0.901

0.046

 ≤ 37

1

1

 >37

1.061

0.420–2.680

2.362

1.014–5.505

Pathological T stage

0.340

–

 pT0–2

1

 pT3–4

1.579

0.618–4.035

Pathological N stage

0.001

0.010

 pN0

1

1

 pN1–2

5.006

1.874–13.368

2.438

1.239–4.797

Lymphovascular invasion

0.007

–

 Negative

1

 Positive

3.086

1.368–6.960

Harvested lymph nodes

–

0.093

 ≥ 12

1

 <12

1.955

0.895–4.270

CRM (mm)

–

<0.001

 >1

1

  ≤ 1

8.609

2.826–26.228

Operative complications

0.573

–

 No

1

 Yes

1.267

0.556–2.890

Neoadjuvant therapy

–

0.476

 No

1

 Yes

1.333

0.605–2.937