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Table 2 Treatment-related adverse events (TRAEs)

From: Safety and efficacy of sintilimab combined with oxaliplatin/capecitabine as first-line treatment in patients with locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma in a phase Ib clinical trial

 

All grade

n (%)

Grade 3–4

n (%)

All TRAEs (n)

20 (100.0)

11 (55.0)

 Platelet count decreased

16 (80.0)

9 (45.0)

 White blood cell count decreased

10 (50.0)

0 (0.0)

 Neutrophil count decreased

10 (50.0)

2 (10.0)

 Hypothyroidism

6 (30.0)

0 (0.0)

 Rash

5 (25.0)

0 (0.0)

 Alanine aminotransferase increased

5 (25.0)

0 (0.0)

 Aspartate aminotransferase increased

4 (20.0)

0 (0.0)

 Anemia

4 (20.0)

0 (0.0)

 Hepatic function abnormal

3 (15.0)

1 (5.0)

 Vomiting

3 (15.0)

0 (0.0)

 Nausea

2 (10.0)

0 (0.0)

 Hyperchlorhydria

2 (10.0)

0 (0.0)

 Thyroid function test abnormal

2 (10.0)

0 (0.0)

 Hypokalemia

2 (10.0)

1 (5.0)

 Hypesthesia

2 (10.0)

0 (0.0)

 Pyrexia

2 (10.0)

0 (0.0)

 Proteinuria

2 (10.0)

0 (0.0)

 γ-glutamyl transferase increased

1 (5.0)

1 (5.0)

 Diarrhea

1 (5.0)

1 (5.0)

 Autoimmune colitis

1 (5.0)

1 (5.0)

 Pneumonitis

1 (5.0)

1 (5.0)

  1. Listed are any grade TRAE found in ≥10% patients, and all grade 3–4 TRAEs