Table 2 Adverse events of CPT-11/NDP chemotherapy
UGT1A1 | Wild-type (24 cases) | Polymorphism (hetero/homo, n = 23/4 cases) | P-value |
|---|---|---|---|
Neutropenia | 7 | 15 | 0.09 |
Grade 3 | 5 | 12 | 0.13 |
Grade 4 | 2 | 3 | > 0.99 |
Febrile neutropenia | 1 | 1 | >  0.99 |
Nausea (> Grade 3) | 1 | 2 | >  0.99 |
Diarrhea (> Grade 3) | 4 | 3 | 0.69 |
Anorexia (> Grade 3) | 0 | 2 | 0.49 |
Thrombocytopenia (> Grade 3) | 0 | 1 | >  0.99 |