Evaluation of radioactive 125I seed implantation for the treatment of refractory malignant tumours based on a CT-guided 3D template-assisted technique: efficacy and safety

Table 5 Multivariate analysis on the factors that affect the treatment prognosis

Factors	n	Univariate			Multivariate
Factors	n	HR	95%CL	P	HR	95%CL	P
Age
< 60 years old	9	1			1
≥ 60 years old	16	0.985	0.546–1.809	0.961	0.853	0.460–1.581	0.621
Gender
Male	17	1			1
Female	8	0.746	0.390–1.425	0.375	0.934	0.457–1.740	0.813
Template type
Coplanar	22
Non-coplanar	3	0.823	0.460–1.581	0.623	0.924	0.461–1.811	0.816
Number of puncture needle
< 10	6	1			1
≥ 10 < 20	9	1.614	0.849–3.068	0.144	1.784	0.673–4.729	0.244
≥ 20	10	1.001	0.484–2.070	0.998	0.669	0.256–1.746	0.411
Number of seed implantation
< 30	7	1			1
≥ 30 < 60	9	1.241	0.765–2.012	0.381	1.024	0.719–1.459	0.896
≥ 60	9	1.567	1.095–2.240	0.067	0.633	0.357–0.892	0.402
Tumor location
Thoracic tumor	7	1			1
Bone and soft tissue tumor	7	0.423	0.219–0.816	0.012	0.147	0.042–0.527	0.003
Abdominal tumor	4	0.167	0.051–0.634	0.008	4.995	2.557–9.582	0.003
Genitourinary tumor	4	0.342	0.192–1.357	0.019	0.297	0.119–0.731	0.007
Lymph node metastasis tumor	2	0.641	0.049–0.829	0.012	0.627	0.047–0.359	0.009
Head and neck cancer	1	0.378	0.161–0.653	0.026	0.254	0.103–0.545	0.001

Values are the risk ratio (95% confidence interval) of the generalized linear model, which reflects that tumor location is the factors affecting prognosis. Model is adjusted for age, gender, number of puncture needle, number of seed implantation, tumor-location. The p-values were defined as< 0.05

ISSN: 1471-2407