Fig. 3
From: The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models
Lung Tumor Rate in FVB/N-SPC-TP53-273H and A/J-SPC-TP53-273H mice. a FVB/N-SPC-TP53-273H and A/J-SPC-TP53-273H mice were sacrificed and analyzed for lung tumor incidence. The rate of tumor formation is shown here in both strains. The A/J-SPC-TP53-273H transgenic mice have an increased rate of lung tumor in all age groups when compared to the FVB/N-SPC-TP53-273H mice. The tumor rate change between both groups is represented by the error bar. b Lung tumor rate observed in A/J non-transgenic (A/J-NT) mice and FVB/N non-transgenic (FVB/N-NT) mice. At age of 13–15 and 16–18 months A/J- NT mice had a more frequent tumor rate when compared to FVB/N-NT mice