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Table 5 Odds ratios (women vs men) for preoperative radiotherapy by age and tumor depth

From: Gender differences in stage at diagnosis and preoperative radiotherapy in patients with rectal cancer

 

Preoperative radiotherapy

Unadjusteda

Adjusteda,b

OR (95%CI)

p- value

OR (95%CI)

p-value

Agec

  < 65 years

0.60 (0.37–0.97)

0.04

0.58 (0.34–0.99)

0.04

  ≥ 65 years

0.96 (0.69–1.31)

0.78

0.90 (0.64–1.25)

0.52

Tumor depthc

 cT1-cT2

1.03 (0.47–2.27)

0.72

1.16 (0.52–2.60)

0.72

 cT3-cT4

0.58 (0.41–0.84)

0.003

0.51 (0.36–0.74)

< 0.0005

 Unknown

0.86 (0.51–1.44)

0.56

0.83 (0.50–1.37)

0.47

  1. a We used generalized estimating equations to estimate the women-to-men odds ratios (ORs)
  2. bAdjusted for Charlson index and distance from anal verge
  3. cTo increase the statistical power, we recoded age into two categories (< 65 and ≥ 65 years) and tumor depth into three categories (cT1-cT2, cT3-cT4 and Unknown)