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Table 5 Odds ratios (women vs men) for preoperative radiotherapy by age and tumor depth

From: Gender differences in stage at diagnosis and preoperative radiotherapy in patients with rectal cancer

  Preoperative radiotherapy
Unadjusteda Adjusteda,b
OR (95%CI) p- value OR (95%CI) p-value
Agec
  < 65 years 0.60 (0.37–0.97) 0.04 0.58 (0.34–0.99) 0.04
  ≥ 65 years 0.96 (0.69–1.31) 0.78 0.90 (0.64–1.25) 0.52
Tumor depthc
 cT1-cT2 1.03 (0.47–2.27) 0.72 1.16 (0.52–2.60) 0.72
 cT3-cT4 0.58 (0.41–0.84) 0.003 0.51 (0.36–0.74) < 0.0005
 Unknown 0.86 (0.51–1.44) 0.56 0.83 (0.50–1.37) 0.47
  1. a We used generalized estimating equations to estimate the women-to-men odds ratios (ORs)
  2. bAdjusted for Charlson index and distance from anal verge
  3. cTo increase the statistical power, we recoded age into two categories (< 65 and ≥ 65 years) and tumor depth into three categories (cT1-cT2, cT3-cT4 and Unknown)