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Table 4 Association of preoperative radiotherapy with various factors in men and women

From: Gender differences in stage at diagnosis and preoperative radiotherapy in patients with rectal cancer

  Preoperative radiotherapy p-value for gender interaction3
Men Women
N n (%) P1 N n (%) P1  
Age    < 0.00052    0.322 0.015
  < 65 years 221 140 (63.3)   108 55 (50.9)   
 65–80 years 245 132 (53.9)   105 56 (53.3)   
  > 80 years 56 17 (30.4)   35 13 (37.1)   
Charlson index    0.05    0.02 0.73
 0 258 154 (59.7)   165 91 (55.2)   
  ≥ 1 264 135 (51.1)   83 33 (39.8)   
Tumor depth    < 0.0005    < 0.0005 0.20
 cT1 - cT2 91 18 (19.8)   55 10 (18.2)   
 cT3 273 211 (77.3)   120 81 (67.5)   
 cT4 28 24 (85.7)   34 23 (67.6)   
 Unknown 130 36 (27.7)   39 10 (25.6)   
Distance from anal verge    < 0.0005    0.01 0.95
  < 5 cm 100 69 (69.0)   57 34 (59.6)   
 5–10 cm 218 141 (64.7)   83 48 (57.8)   
  > 10 cm 167 67 (40.1)   90 37 (41.1)   
 Unknown 37 12 (32.4)   18 5 (27.8)   
Histological classification    0.20    0.63 0.97
 Adenocarcinoma 474 267 (56.3)   208 103 (49.5)   
 Mucinous adenocarcinoma 18 8 (44.4)   14 7 (50.0)   
 Undifferentiated carcinomas 6 1 (16.7)   4 1 (25.0)   
 Unknown 24 13 (54.2)   22 13 (59.1)   
  1. 1 Pearson chi-square test
  2. 2 Chi-square test for trend
  3. 3 Likelihood ratio test for gender interaction