Table 4 Association of preoperative radiotherapy with various factors in men and women
Preoperative radiotherapy | p-value for gender interaction3 | ||||||
|---|---|---|---|---|---|---|---|
Men | Women | ||||||
N | n (%) | P1 | N | n (%) | P1 | ||
Age | < 0.00052 | 0.322 | 0.015 | ||||
< 65 years | 221 | 140 (63.3) | 108 | 55 (50.9) | |||
65–80 years | 245 | 132 (53.9) | 105 | 56 (53.3) | |||
> 80 years | 56 | 17 (30.4) | 35 | 13 (37.1) | |||
Charlson index | 0.05 | 0.02 | 0.73 | ||||
0 | 258 | 154 (59.7) | 165 | 91 (55.2) | |||
≥ 1 | 264 | 135 (51.1) | 83 | 33 (39.8) | |||
Tumor depth | < 0.0005 | < 0.0005 | 0.20 | ||||
cT1 - cT2 | 91 | 18 (19.8) | 55 | 10 (18.2) | |||
cT3 | 273 | 211 (77.3) | 120 | 81 (67.5) | |||
cT4 | 28 | 24 (85.7) | 34 | 23 (67.6) | |||
Unknown | 130 | 36 (27.7) | 39 | 10 (25.6) | |||
Distance from anal verge | < 0.0005 | 0.01 | 0.95 | ||||
< 5 cm | 100 | 69 (69.0) | 57 | 34 (59.6) | |||
5–10 cm | 218 | 141 (64.7) | 83 | 48 (57.8) | |||
> 10 cm | 167 | 67 (40.1) | 90 | 37 (41.1) | |||
Unknown | 37 | 12 (32.4) | 18 | 5 (27.8) | |||
Histological classification | 0.20 | 0.63 | 0.97 | ||||
Adenocarcinoma | 474 | 267 (56.3) | 208 | 103 (49.5) | |||
Mucinous adenocarcinoma | 18 | 8 (44.4) | 14 | 7 (50.0) | |||
Undifferentiated carcinomas | 6 | 1 (16.7) | 4 | 1 (25.0) | |||
Unknown | 24 | 13 (54.2) | 22 | 13 (59.1) | |||