Table 2 Association of stage IV disease with various factors in men and women
Stage IV | |||||||
|---|---|---|---|---|---|---|---|
Men | Women | p-value for gender interaction3 | |||||
N | n (%) | P1 | N | n (%) | P1 | ||
Age | 0.382 | 0.202 | 0.80 | ||||
< 65 years | 221 | 17 (7.7) | 108 | 14 (13.0) | |||
65–80 years | 245 | 14 (5.7) | 105 | 10 (9.5) | |||
> 80 years | 56 | 3 (5.4) | 35 | 2 (5.7) | |||
Charlson index | 0.44 | 0.10 | 0.33 | ||||
0 | 258 | 19 (7.4) | 165 | 21 (12.7) | |||
≥ 1 | 264 | 15 (5.7) | 83 | 5 (6.0) | |||
Screening | 0.43 | 0.07 | 0.002 | ||||
No | 429 | 30 (7.0) | 201 | 17 (8.5) | |||
Yes | 68 | 2 (2.9) | 30 | 5 (16.7) | |||
Unknown | 25 | 2 (8.0) | 17 | 4 (23.5) | |||
Diagnostic delay | 0.16 | 0.37 | 0.004 | ||||
≤ 3 months | 374 | 29 (7.8) | 155 | 13 (8.4) | |||
> 3 months | 83 | 2 (2.4) | 59 | 8 (13.6) | |||
Unknown | 65 | 3 (4.6) | 34 | 5 (14.7) | |||
Distance from anal verge | 0.34 | 0.83 | 0.67 | ||||
< 5 cm | 100 | 3 (3.0) | 57 | 5 (8.8) | |||
5–10 cm | 218 | 15 (6.9) | 83 | 10 (12.0) | |||
> 10 cm | 167 | 12 (7.2) | 90 | 10 (11.1) | |||
Unknown | 37 | 4 (10.8) | 18 | 1 (3.8) | |||
Histological classification | 0.49 | 0.04 | 0.25 | ||||
Adenocarcinoma | 474 | 31 (6.5) | 208 | 18 (8.7) | |||
Mucinous adenocarcinoma | 18 | 0 (0) | 14 | 1 (7.1) | |||
Undifferentiated carcinomas | 6 | 1 (16.7) | 4 | 1 (25.0) | |||
Unknown | 24 | 2 (8.3) | 22 | 6 (27.3) | |||
Preoperative radiotherapy | 0.52 | 0.10 | 0.21 | ||||
No | 233 | 17 (7.3) | 124 | 17 (13.7) | |||
Yes | 289 | 17 (5.9) | 124 | 9 (7.3) | |||