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Table 1 Characteristics of Training and Testing Dataset of Nested Case Control Study Based on EPIC-Italy Cohort

From: A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibility

Characteristics

Entire Dataset

Training Dataset

Testing Dataset

Cases

Control

Cases

Control

Cases

Control

Total

166

424

117

297

49

127

Age, Mean (SD)

55.07 (6.73)

53.23 (7.19)

55.94 (6.73)

53.08 (7.20)

55.25 (6.62)

53.56 (7.20)

<  60

128 (26.9)

348 (73.1)

89 (26.4)

245 (73.4)

10 (27.5)

103 (72.5)

≥ 60

38 (33.3)

76 (66.7)

28 (35.0)

52 (65.0)

39 (29.4)

24 (70.6)

Gender

 Male

87 (52.4)

84 (19.8)

55 (47.4)

61 (52.6)

32 (58.2)

23 (41.8)

 Female

79 (47.6)

340 (80.2)

62 (20.8)

236 (79.2)

17 (14.0)

104 (86.2)

Time-to-diagnosis (years)

  < 6

80 (48.2)

NA

56 (47.9)

NA

24 (49.0)

NA

  ≥ 6

86 (51.8)

NA

61 (52.1)

NA

25 (51.0)

NA

  1. Abbreviations: NA Not applicable, SD Standard deviation