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Table 1 Characteristics of Training and Testing Dataset of Nested Case Control Study Based on EPIC-Italy Cohort

From: A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibility

Characteristics Entire Dataset Training Dataset Testing Dataset
Cases Control Cases Control Cases Control
Total 166 424 117 297 49 127
Age, Mean (SD) 55.07 (6.73) 53.23 (7.19) 55.94 (6.73) 53.08 (7.20) 55.25 (6.62) 53.56 (7.20)
<  60 128 (26.9) 348 (73.1) 89 (26.4) 245 (73.4) 10 (27.5) 103 (72.5)
≥ 60 38 (33.3) 76 (66.7) 28 (35.0) 52 (65.0) 39 (29.4) 24 (70.6)
Gender
 Male 87 (52.4) 84 (19.8) 55 (47.4) 61 (52.6) 32 (58.2) 23 (41.8)
 Female 79 (47.6) 340 (80.2) 62 (20.8) 236 (79.2) 17 (14.0) 104 (86.2)
Time-to-diagnosis (years)
  < 6 80 (48.2) NA 56 (47.9) NA 24 (49.0) NA
  ≥ 6 86 (51.8) NA 61 (52.1) NA 25 (51.0) NA
  1. Abbreviations: NA Not applicable, SD Standard deviation