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Fig. 5 | BMC Cancer

Fig. 5

From: PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts

Fig. 5

Area under the curve describing migration behavior in melanoma and healthy tissue cells. Melanoma cells a A375M (n = 4), b BIMA (n = 4), c ILSA (n = 4), d Mel624 (n = 4), e PMelL (n = 4), f RERO (n = 4) and healthy tissue cell cultures g SBLF9 (n = 5), h SBLF7 (n = 5) treated w/o 50 nmol/l talazoparib, w/o 2 Gy IR or w/o 2500 nmol/l niraparib, w/o 2 Gy IR; the area under the curve of the relative scratch area within 48 h describing migration behavior (AUC = 2 = no migration, AUC < 2 = migration); * = p < 0.05, ** = p < 0.01, *** = p < 0.001; each value represents mean ± SD

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