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Table 4 Multivariate analysis of baseline parameters associated with PFS

From: Education level as a predictor of survival in patients with multiple myeloma

Variables PFS
HR (95% CI) P
All patients
 Education level: high vs low 0.50 (0.34–0.72) < 0.001
 LDH: ≥240 vs < 240 U/L 2.08 (1.48–2.94) < 0.001
 Cytogenetics: high risk vs standard risk 1.77 (1.28–2.45) 0.001
 Receipt of transplant: no vs yes 2.70 (1.95–3.74) < 0.001
Patients < 60 years
 Education level: high vs low 0.47 (0.29–0.74) 0.002
 LDH: ≥240 vs < 240 U/L 2.45 (1.52–3.95) 0.001
 Cytogenetics: high risk vs standard risk 1.85 (1.18–2.90) 0.007
 Receipt of transplant: no vs yes 2.00 (1.20–3.35) 0.008
 Regular treatment: no vs yes 2.08 (1.53–3.73) 0.015
Patients ≥ 60 years
 Education level: high vs low 0.53 (0.29–0.98) 0.043
 LDH: ≥240 vs < 240 U/L 1.81 (1.10–3.00) 0.020
 Cytogenetics: high risk vs standard risk 1.68 (1.03–2.72) 0.037
 Receipt of transplant: no vs yes 2.38 (1.36–4.17) 0.002
  1. PFS progression-free survival, HR hazard ratio, CI confidence interval, LDH lactate dehydrogenase