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Table 4 Multivariate analysis of baseline parameters associated with PFS

From: Education level as a predictor of survival in patients with multiple myeloma

Variables

PFS

HR (95% CI)

P

All patients

 Education level: high vs low

0.50 (0.34–0.72)

< 0.001

 LDH: ≥240 vs < 240 U/L

2.08 (1.48–2.94)

< 0.001

 Cytogenetics: high risk vs standard risk

1.77 (1.28–2.45)

0.001

 Receipt of transplant: no vs yes

2.70 (1.95–3.74)

< 0.001

Patients < 60 years

 Education level: high vs low

0.47 (0.29–0.74)

0.002

 LDH: ≥240 vs < 240 U/L

2.45 (1.52–3.95)

0.001

 Cytogenetics: high risk vs standard risk

1.85 (1.18–2.90)

0.007

 Receipt of transplant: no vs yes

2.00 (1.20–3.35)

0.008

 Regular treatment: no vs yes

2.08 (1.53–3.73)

0.015

Patients ≥ 60 years

 Education level: high vs low

0.53 (0.29–0.98)

0.043

 LDH: ≥240 vs < 240 U/L

1.81 (1.10–3.00)

0.020

 Cytogenetics: high risk vs standard risk

1.68 (1.03–2.72)

0.037

 Receipt of transplant: no vs yes

2.38 (1.36–4.17)

0.002

  1. PFS progression-free survival, HR hazard ratio, CI confidence interval, LDH lactate dehydrogenase