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Table 1 Characteristics of 58 NM patients

From: Detection of genes mutations in cerebrospinal fluid circulating tumor DNA from neoplastic meningitis patients using next generation sequencing

Clinical characteristics # of patients (%)
Gender
 Male 27 (46.6)
 Female 31 (53.4)
Age (year)
 Median (range) 55 (23–77)
Primary cancer
 Lung cancer 42 (72.4)
 Gastric cancer 4 (6.9)
 Breast cancer 3 (5.2)
 Rectal cancer 2 (3.4)
 Prostatic cancer 1 (1.7)
 Parotid carcinoma 1 (1.7)
 Lymphoma 1 (1.7)
 Glioblastoma 1 (1.7)
 Unknown malignancy 3 (5.2)
First symptom with NM 10 (17.2)
Diagnostic basis
 CSF cytology 44 (75.9)
 Neuroimaging findings 8 (13.8)
 CSF ctDNA 6 (10.3)
Treatment regimen (CSF samples)
 Intrathecal chemotherapy and systemic therapy 30 (48.4)
 Intrathecal chemotherapy without systemic therapy 11 (17.7)
 Systemic therapy without intrathecal chemotherapy
 No therapy
12 (19.4)
9 (28.5)
Hydrocephalus
 Yes 5 (8.6)
 No 53 (91.4)