Skip to main content

Table 4 Detailed sensitivity and specificity report for EGFR mutation predicted probability cut-points of 0.2 and 0.6

From: Development and validation of a predictive model for estimating EGFR mutation probabilities in patients with non-squamous non-small cell lung cancer in New Zealand

 

Development group

Validation group

0.2

0.6

0.2

0.6

Sensitivity

68.27%

21.69%

63.33%

23.33%

Specificity

78.21%

95.25%

79.20%

96.49%

Positive predictive value

45.70%

55.10%

40.71%

60.00%

Negative predictive value

90.17%

81.91%

90.54%

84.80%

Informedness index a

0.46

0.17

0.43

0.2

  1. a Informedness index is calculated as sensitivity+specificity-1. Interpretation: 0 means the test is useless, 1 means the test is perfect, and a value of > 0 means an appropriate use of information [Reference: Youden WJ. Index for rating diagnostic tests. Cancer. 1950;3(1):32–5]
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us