Fig. 2

IMMUNEPOTENT CRP induces caspase-independent cell death in a ROS-dependent manner in HeLa and MCF-7 cells. a. Cell death was evaluated in HeLa (left) and MCF-7 cells (right) left alone or pretreated with QVD.oph before ICRP treatment (24 h). b. Effect on cell death of HeLa (left) and MCF-7 cells (right) left alone or pretreated with NAC before ICRP treatment (24 h). c. ROS production was measured in HeLa (left) and MCF-7 cells (right) left alone or pretreated with NAC before ICRP treatment (24 h), through DCFDA staining. The charts represent the means (± SD) of triplicates of at least three independent experiments