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Table 2 Univariate and multivariate analysis of OS

From: Management of medically inoperable and tyrosine kinase inhibitor-naïve early-stage lung adenocarcinoma with epidermal growth factor receptor mutations: a retrospective multi-institutional analysis

Characteristics Univariate analyses Multivariate analyses
P HR 95% CI lower 95% CI upper P HR 95% CI lower 95% CI upper
Age (Continuous) 0.688 0.996 0.977 1.015     
Gender
 Male   1.000       
 Female 0.872 0.972 0.686 1.376     
Nodal status
 N0   1.000       
 N1/N2 0.074 1.426 0.966 2.107     
Stages
 I   1.000       
 II 0.110 1.592 0.900 2.818     
 III < 0.001 2.756 1.655 4.588 0.002 2.314 1.368 3.914
RT strategy
 SBRT   1.000       
 EBRT 0.015 2.344 1.184 4.642 0.023 2.289 1.120 4.676
Therapeutic strategy
 TKI alone   1.000       
 R + TKI < 0.001 0.466 0.325 0.669 < 0.001 0.420 0.287 0.614
  1. HR Hazard ratio, CI Confidence interval, SBRT Stereotactic body radiation therapy, EBRT External beam radiation therapy, R + TKI Combined radiation and TKI
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