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Table 2 Univariate and multivariate analysis of OS

From: Management of medically inoperable and tyrosine kinase inhibitor-naïve early-stage lung adenocarcinoma with epidermal growth factor receptor mutations: a retrospective multi-institutional analysis

Characteristics

Univariate analyses

Multivariate analyses

P

HR

95% CI lower

95% CI upper

P

HR

95% CI lower

95% CI upper

Age (Continuous)

0.688

0.996

0.977

1.015

    

Gender

 Male

 

1.000

      

 Female

0.872

0.972

0.686

1.376

    

Nodal status

 N0

 

1.000

      

 N1/N2

0.074

1.426

0.966

2.107

    

Stages

 I

 

1.000

      

 II

0.110

1.592

0.900

2.818

    

 III

< 0.001

2.756

1.655

4.588

0.002

2.314

1.368

3.914

RT strategy

 SBRT

 

1.000

      

 EBRT

0.015

2.344

1.184

4.642

0.023

2.289

1.120

4.676

Therapeutic strategy

 TKI alone

 

1.000

      

 R + TKI

< 0.001

0.466

0.325

0.669

< 0.001

0.420

0.287

0.614

  1. HR Hazard ratio, CI Confidence interval, SBRT Stereotactic body radiation therapy, EBRT External beam radiation therapy, R + TKI Combined radiation and TKI