Table 2 Top statistically related signaling pathways to miR-584 targetome obtained from KEGG database through DAVID tool
From: Fluctuating expression of miR-584 in primary and high-grade gastric cancer
Rank | KEGG Pathway | Number of genes (%) | P* |
|---|---|---|---|
1 | Pathways in cancer | 21 (2.9) | 5.4EÂ2 |
2 | Regulation of actin cytoskeleton | 19 (2.6) | 3.4EÂ3 |
3 | Focal adhesion | 17 (2.4) | 9.1EÂ3 |
4 | Ubiquitin mediated proteolysis | 15 (2.1) | 1.6EÂ3 |
5 | Chemokine signaling pathway | 14 (1.9) | 4.7EÂ2 |
6 | Endocytosis | 13 (1.8) | 8.1EÂ2 |
7 | Fc gamma RÂmediated phagocytosis | 12 () | 1.8EÂ3 |
8 | Chronic myeloid leukemia | 11 (1.7) | 9.9EÂ4 |
9 | Insulin signaling pathway | 11 (1.5) | 5.4EÂ2 |
10 | Wnt signaling pathway | 11 (1.5) | 9.8EÂ2 |
11 | Pancreatic cancer | 10 (1.4) | 2.8EÂ3 |
12 | Adherens junction | 10 (1.4) | 4.4EÂ3 |
13 | Vascular smooth muscle contraction | 9 (1.2) | 9.4EÂ2 |
14 | Colorectal cancer | 9 (1.2) | 2.3EÂ2 |
15 | TGFÂbeta signaling pathway | 9 (1.2) | 2.8EÂ2 |
16 | Oocyte meiosis | 9 (1.2) | 8.7EÂ2 |
17 | LongÂterm potentiation | 8 (1.1) | 2.2EÂ2 |
18 | Phosphatidylinositol signaling system | 8 (1.1) | 3.4EÂ2 |
19 | Endometrial cancer | 7 (1) | 2.0EÂ2 |
20 | Acute myeloid leukemia | 7 (1) | 3.3EÂ2 |
21 | Melanoma | 7 (1) | 7.4EÂ2 |
22 | B cell receptor signaling pathway | 7 (1) | 9.1EÂ2 |
23 | VEGF signaling pathway | 7 (1) | 9.1EÂ2 |
24 | NonÂsmall cell lung cancer | 6 (0.8) | 7.3EÂ2 |
25 | DorsoÂventral axis formation | 4 (0.6) | 8.4EÂ2 |