Table 5 Late postoperative outcome
N (%) | Overall Population | Symptomatic AL (SAL) | Asymptomatic AL (AAL) | Without AL (WAL) | P |
|---|---|---|---|---|---|
200 (100) | 29 (14.5) | 10 (5.0) | 161 (80.5) | ||
Oncological results | |||||
Adjuvant chemotherapy, n (%) | 52 (26.0) | 7 (24.1) | 1 (10.0) | 44 (27.3) | 0.465 |
Recurrence, n (%) | |||||
Local | 10 (5.0) | 2 (6.9) | 0 | 8 (5.0) | |
Distance | 34 (17.0) | 3 (10.3) | 0 | 31 (19.3) | 0.170 |
Total patients with recurrence | 39 (19.5) | 4 (13.8) | 0 | 35 (21.7) | |
Time to recurrence (month), median ± IQR | 10.7 (8.8–18.8) | 7.0 (6.0–8.1) | 0 | 11.8 (9.6–19.8) | 0.173 |
Median of follow up (months) ± IQR | 38.5 (17.2–65.6) | 34.5 (17.1–66.5) | 55.7 (28.8–61.9) | 38.1 (16.7–65.5) | |
Overall survival at 3 years | 95.5% | 82.9% | 100% | 94.7% | 0.527 |
Overall survival at 5 years | 91.5% | 77% | 100% | 88.3% | |
Disease free survival at 3 years | 81.5% | 86.6% | 100% | 76% | 0.480 |
Disease free survival at 5 years | 80.5% | 84% | 100% | 70% | |
Functional results | |||||
Permanent stoma, n (%) | 31 (15.5) | 13 (44.8) | 3 (30.0) | 15 (9.3) | < 0.001 |
Ileostomy | 18 (9.0) | 7 (24.1) | 1 (10.0) | 11 (6.8) | |
Colostomy | 13 (6.5) | 6 (20.7) | 2 (20.0) | 4 (2.5) | |
Other late complications, n (%) | < 0.001 | ||||
Stenosis | 24 | 6 | 1 | 17 | |
Hernia | 16 | 5 | 4 | 7 | |
Occlusion | 3 | 1 | 0 | 2 | |
Mean of quality of life assessments | |||||
LARS Score | 26,2 ± 12,8 | 34,3 ± 4,0 | 28,8 ± 14,9 | 25,1 ± 13,0 | 0.522 |
Wexner Score | 7,3 ± 4,8 | 10,3 ± 0,6 | 11,4 ± 3,8 | 6,4 ± 4,7 | 0.049 |
IIEF5 | 10,0 ± 8,9 | 18,0 ± 1,4 | 2,3 ± 2,3 | 10,4 ± 9,2 | 0.187 |
SF36 | 98,8 ± 10,5 | 105,0 ± 7,9 | 99,2 ± 5,4 | 98,2 ± 11,2 | 0.446 |
EORTC QLQ-C30 | 53,9 ± 11,4 | 49,3 ± 3,2 | 62,4 ± 14,5 | 53,0 ± 11,0 | 0.077 |
EuroQol | 69,0 ± 18,9 | 75,0 ± 5,0 | 59,0 ± 18,2 | 69,9 ± 19,6 | 0.111 |
FIQL | 86,8 ± 20,6 | 81,3 ± 3,5 | 74,2 ± 22,0 | 89,2 ± 20,8 | 0.136 |
EORTC QLQ-MY20 | 28,7 ± 7,0 | 28,3 ± 1,5 | 31,0 ± 7,1 | 28,4 ± 7,4 | 0.685 |