Fig. 1

Histopathological features of tumor necrosis in primary solitary small hepatocellular carcinoma. Tumor necrosis in sHCC consisted of homogenous clusters of sheets of degenerating and dead cells, or coalescing groups of cells forming a coagulum, containing nuclear and cytoplasmic debris, with membrane integrity, intracellular organelle swelling (a-b, hematoxylin and eosin [H&E], magnification × 40; C-D, H&E, × 200)