Fig. 7
Slowing of MDA-MB-231 xenograft tumor by BK channel opener. a: Three paired-tumors of similar sizes (C1/T1, C2/T2, C3/T3) are shown to illustrate the inhibitory effects of BMS-191011 in tumor growth. Ultrasound imaging was performed once a week to calculate the tumor volume (mm3) for four weeks. A reconstruction of the tumor volume from ultrasound imaging is shown in the inset. b: Final average tumor volume in control (n = 8) and treated groups at week 8 (n = 8). *: p < 0.05 (t-Test was performed, two-tailed p = 0.0356, t = 2.32592)