Table 4 Characteristics of patients according to DSS and OS
From: Neutrophil-lymphocyte ratio associated with poor prognosis in oral cancer: a retrospective study
Variables | n (%) | 5-year DSS (%) | P value | 5-year OS (%) | P value |
|---|---|---|---|---|---|
Sex | |||||
 Male | 246 (56.8) | 83.1 | 0.684 * | 74.6 | 0.126 * |
 Female | 187 (43.2) | 84.8 |  | 80.5 |  |
Age | |||||
 Range (Years) | 22–98 |  |  |  |  |
 Mean ± SD | 66.3 ± 13.5 |  |  |  |  |
  ≥ 64 | 173 (40.0) | 79.9 | 0.120 * | 73.7 | 0.608 * |
  ≤ 65 | 260 (60.0) | 86.6 |  | 79.6 |  |
Smoking history | |||||
 No | 219 (50.6) | 88.2 | 0.548 * | 82.5 | 0.179 * |
 Yes | 69 (15.9) | 85.3 |  | 76.7 |  |
 Unknown | 145 (33.5) |  |  |  |  |
Alcohol consumption | |||||
 No | 152 (35.1) | 83.9 | 0.105 * | 77.3 | 0.391 * |
 Yes | 131 (30.3) | 91.2 |  | 84.6 |  |
 Unknown | 150 (34.6) |  |  |  |  |
Performance status | |||||
 0 | 227 (52.4) | 85.2 | 0.274 * | 79.6 | 0.025 * |
  ≥ 1 | 202 (46.7) | 81.9 |  | 74.3 |  |
 unknown | 4 (0.9) |  |  |  |  |
Subsite | |||||
 Tongue | 211 (48.7) | 85.4 | 0.311 * | 80.2 | 0.083 * |
 Other | 222 (51.3) | 82.2 |  | 73.9 |  |
T classification | |||||
 1, 2 | 301 (69.5) | 88.5 | <  0.001 * | 83.1 | <  0.001 * |
 3, 4a/b | 132 (30.5) | 72.2 |  | 62.4 |  |
N classification | |||||
 0 | 296 (68.4) | 91.6 | <  0.001 * | 85.6 | <  0.001 * |
 Others | 137 (31.6) | 66.4 |  | 58.5 |  |
NLR | |||||
 Low (2.22 <) | 233 (53.8) | 91.4 | <  0.001 * | 84.6 | < 0.001 * |
 High (2.22 ≥) | 200 (46.2) | 75.5 |  | 68.8 |  |
LMR | |||||
 Low (4.35 <) | 253 (58.4) | 76.3 | < 0.001 * | 70.0 | 0.001 * |
 High (4.35 ≥) | 180 (41.6) | 89.1 |  | 82.1 |  |
PLR | |||||
 Low (134.3 <) | 240 (55.4) | 86.6 | 0.044 * | 78.4 | 0.232 * |
 High (134.3 ≥) | 193 (44.6) | 80.6 |  | 75.6 |  |
Pathological status | |||||
 Pathological extra nodal metastasis |  |  |  |  |  |
  ENE - | 89 (56.3) | 72.8 | 0.004 * | 63.7 | 0.012 * |
  ENE + | 69 (43.7) | 50.7 |  | 42.4 |  |
 Number of pathological lymph node metastases | |||||
  0, 1 | 173 (63.6) | 84.7 | < 0.001 * | 78.1 | < 0.001 * |
   ≥ 2 | 99 (36.4) | 60.8 |  | 50.1 |  |
 Surgical margins | |||||
  Negative | 314 (72.5) | 85.5 | 0.030 * | 78.7 | 0.043 * |
  Involved margins | 112 (25.9) | 79.1 |  | 72.1 |  |
  unknown | 7 (1.6) |  |  |  |  |
 Histological differentiation | |||||
  Well differentiated | 261 (60.3) | 91.5 | < 0.001 * | 83.3 | 0.001 * |
  Moderately or poorly differentiated | 168 (38.8) | 71.7 |  | 67.0 |  |
  unknown | 4 (0.9) |  |  |  |  |