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Table 2 Characteristics of patients according to LMR

From: Neutrophil-lymphocyte ratio associated with poor prognosis in oral cancer: a retrospective study

Variables

LMR

P value

Low, n (%)

High, n (%)

Number of patients

180 (41.6)

253 (58.4)

 

Sex

 Male

112 (62.2)

134 (53.0)

0.062 *

 Female

68 (37.8)

119 (47.0)

 

Age

 Range (Years)

22–92

23–98

 

 Mean ± SD

67.8 ± 12.9

65.3 ± 13.8

0.057 **

  ≥ 64

66 (36.7)

107 (42.3)

0.273 *

  ≤ 65

114 (63.3)

146 (57.7)

 

Smoking history

 No

94 (52.2)

125 (49.4)

0.680 *

 Yes

32 (17.8)

37 (14.6)

 

 Unknown

54 (30.0)

91 (36.0)

 

Alcohol consumption

 No

63 (35.0)

89 (35.2)

0.282 *

 Yes

63 (35.0)

68 (26.9)

 

 Unknown

54 (30.0)

96 (37.9)

 

Performance status

 0

78 (43.3)

149 (58.9)

0.002 *

  ≥ 1

100 (55.6)

102 (40.3)

 

 Unknown

2 (1.1)

2 (0.8)

 

Subsite

 Tongue

75 (41.7)

136 (53.8)

0.015 *

 Other

105 (58.3)

117 (46.2)

 

T classification

 1, 2

111 (61.7)

190 (75.1)

0.003 *

 3, 4a/b

69 (38.3)

63 (24.9)

 

N classification

 0

110 (61.1)

186 (73.5)

0.007 *

 Others

70 (38.9)

67 (26.5)

 

Pathological status

 Pathological extranodal extension

  ENE -

41 (52.6)

48 (60.0)

0.423 *

  ENE +

37 (47.4)

32 (40.0)

 

 Number of pathological lymph node metastases

  0, 1

74 (58.3)

99 (68.3)

0.101 *

   ≥ 2

53 (41.7)

46 (31.7)

 

 Surgical margins

  Negative

133 (73.9)

194 (76.7)

0.417 *

  Involved margins

45 (25.0)

54 (21.3)

 

  Unknown

2 (1.1)

5 (2.0)

 

 Histological differentiation

  Well differentiated

107 (59.4)

154 (60.9)

0.736 *

  Moderately or poorly differentiated

72 (40.0)

96 (37.9)

 

  Unknown

1 (0.6)

3 (1.2)

 
  1. ENE Extranodal extension; LMR Lymphocyte-to-monocyte ratio
  2. *: Fisher’s exact test **: Mann–Whitney U test