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Fig. 5 | BMC Cancer

Fig. 5

From: The microRNA-130a-5p/RUNX2/STK32A network modulates tumor invasive and metastatic potential in non-small cell lung cancer

Fig. 5

RUNX2 augments the expression of STK32A in NSCLC cells. a the putative binding sites between RUNX2 and STK32A by an online website; b the binding relationship between RUNX2 and STK32A in A549 cells corroborated by ChIP; c the upregulation of STK32A in lung adenocarcinoma predicted by an online tool and proved in NSCLC cells (one-way ANOVA, *p < 0.05). pcDNA RUNX2 or sh-RUNX2 was delivered into A549 and SK-MES-1 cells. d the successful transfection confirmed by RT-qPCR (one-way ANOVA, *p < 0.05); E, the mRNA expression of STK32A evaluated by RT-qPCR (one-way ANOVA, *p < 0.05). The data are displayed in the form of mean ± SD from three independent experiments

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BMC Cancer

ISSN: 1471-2407

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