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Fig. 5 | BMC Cancer

Fig. 5

From: Altered staining patterns and expression level of Engrailed-2 in benign prostatic hyperplasia and prostate Cancer predict prostatic disease progression

Fig. 5

RT-qPCR assay of mTOR, PTEN, VEGF, EGFR and EN2. a. Relative transcription levels of mTOR, PTEN, VEGF, EGFR and EN2 in 25 PC cases. b. Relative transcription levels of mTOR, PTEN, VEGF, EGFR and EN2 in 25 BPH cases. Each dot represented one case. The mean of relative transcription levels of EN2 was the highest among the mean of relative transcription levels of the other four targets both in PC and BPH cases (P < 0.01). c. The negative correlation between PTEN and EN2 in 25 PC cases (R = -0.399, P = 0.048). No significant difference among other tested markers. d. The positive correlation between VEGF and EN2 in 25 BPH cases (R = -0.47, P = 0.019). No significant difference among other tested markers

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