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Table 3 Multivariate analyses involving the prognostic modela with nodal status, tumor size, intrinsic classification and histological grade

From: A prognostic model based on cell-cycle control predicts outcome of breast cancer patients

 

HRb

p

CI

All patients (n = 781)

 Model

8.4

< 0.0001

3.4–20.7

 Nodal status

4.3

< 0.0001

2.6–7.0

 Tumor size

 

ns.

 

 Tumor grade

 

ns.

 

 Intrinsic classification

 

ns.

 

N+ patients (n = 350)

 Model

6.5

0.0003

2.3–17.9

 Tumor size

 

ns.

 

 Tumor grade

 

ns.

 

 Intrinsic classification

 

ns.

 

N- patients (n = 431)

 Model

19.5

0.006

2.3–163.8

 Tumor size

 

ns.

 

 Tumor grade

 

ns.

 

 Intrinsic classification

 

ns.

 
  1. (≥1% of cancer cells) and Cdk1 (≥10% of cancer cells)
  2. aHigh expression for Securin (≥10% of cancer cells), Separase
  3. bThe hazard ratio of breast cancer death
  4. ns not statistically significant
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BMC Cancer

ISSN: 1471-2407

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