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Table 4 Blood parameters of chemotherapy cycles with short-term fasting or normocaloric diet comparing cycles of mSTF (n = 56) with cycles of NC (n = 62)

From: Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study

 UnitNCmSTFPE ± SD95% CIP-Value
Blood count
 Leukocytes103/μl6.67 ± 2.236.09 ± 2.25− 0.25 ± 0.30−0.84 – 0.350.406
 Thromobytes103/μl288.2 ± 76.6306.6 ± 76.94.85 ± 10.76−16.56 – 26.250.654
 Erythrocytes103/μl3.91 ± 0.473.95 ± 0.370.11 ± 0.06−0.01 – 0.230.071
 Haemoglobing/dl11.7 ± 1.411.6 ± 1.10.18 ± 0.18−0.19 – 0.540.337
 Haematocrit%33.5 ± 3.933.1 ± 2.90.31 ± 0.52−0.72 – 1.330.553
 MCHpg29.9 ± 1.529.5 ± 1.6−0.38 ± 0.13−0.63 – (− 0.13)0.004
 MCV10− 9 μl85.7 ± 4.084.1 ± 3.7−1.68 ± 0.33−2.33 – (− 1.02)< 0.001
 MCHCg/dl34.9 ± 0.935.1 ± 0.90.23 ± 0.14− 0.05 – 0.510.109
 Neutrophils103/μl4.70 ± 2.204.29 ± 2.24−0.17 ± 0.30−0.76 – 0.430.581
 Lymphocytes%21.0 ± 10.719.7 ± 12.4−0.89 ± 1.32− 3.50 – 1.730.503
 Monocytes%8.22 ± 4.7010.1 ± 5.30.90 ± 0.72−0.52 – 2.330.210
 Eosinophils%0.71 ± 1.290.51 ± 1.18−0.05 ± 0.19−0.42 – 0.330.813
 Basophils%0.68 ± 0.760.74 ± 0.59−0.02 ± 0.10−0.18 – 0.220.860
Electrolytes
 Potassiummmol/l4.29 ± 0.424.28 ± 0.32−0.01 ± 0.07−0.15 – 0.120.845
 Sodiummmol/l139.2 ± 2.2137.9 ± 3.3− 1.17 ± 0.42− 2.0 – (− 0.33)0.007
 Calciummmol/l2.33 ± 0.142.34 ± 0.150.02 ± 0.03−0.04 – 0.070.561
 Magnesiummmol/l0.80 ± 0.070.78 ± 0.07−0.0 ± 0.01−0.02 – 0.020.840
Liver and kidney parameters
 Ureamg/dl26.9 ± 10.025.3 ± 10.6− 1.087 – 1.34−4.54 – 0.790.165
 Creatininemg/dl0.71 ± 0.160.72 ± 0.190.02 ± 0.01−0.01 – 0.050.171
 Uric acidmg/dl4.44 ± 1.335.98 ± 1.791.35 ± 0.171.01–1.68< 0.001
 Bilirubinmg/dl0.33 ± 0.250.29 ± 0.110.01 ± 0.03− 0.05 – 0.070.305
 GOTU/l24.2 ± 8.725.0 ± 7.21.38 ± 1.48− 1.56 – 4.320.353
 GPTU/l22.4 ± 11.823.5 ± 12.2−0.10 ± 1.46−3.01 – 2.810.947
 APg/dl71.4 ± 22.073.6 ± 25.0− 1.96 ± 2.29−6.52 – 2.580.392
 Albuming/dl4.31 ± 0.354.29 ± 0.320.02 ± 0.06− 0.09 – 0.130.741
 CRPmg/l5.57 ± 4.938.1 ± 13.50.87 ± 1.95− 3.0 – 4.730.657
Hormones
 TSHμU/ml1.05 ± 0.741.03 ± 0.73−0.1 ± 0.07−0.24 – 0.050.188
 fT3pmol/l4.21 ± 0.813.75 ± 0.76−0.47 ± 0.09−0.64 – (− 0.30)< 0.001
 Ft4pmol/l15.5 ± 2.716.4 ± 2.90.82 ± 0.370.09–1.550.028
 Insulinpmol/l252.7 ± 372.8140.1 ± 252.4− 169.4 ± 44.1− 257.1 – (− 81.8)< 0.001
 IGF-1ng/ml127.7 ± 55.797.8 ± 46.4− 33.3 ± 5.4−44.1 – (− 22.5)< 0.001
  1. Values are shown as mean ± SD. Due to missing data, we included data of 61 cycles of NC and 56 cycles of mSTF in this analysis. Abbreviations: AP alkaline phosphatase, CRP C-reactive protein, GOT glutamic-oxaloacetic transaminase, GPT glutamic-pyruvic transaminase, IGF-1 insulin-like growth factor 1, MCH mean corpuscular haemoglobin, MCHC mean corpuscular haemoglobin concentration, MCV mean corpuscular volume, fT3 free triiodothyronine, fT4 free thyroxine, TSH thyroid stimulating hormone