Plasma omega-3 polyunsaturated fatty acids and recurrence of endometrial cancer

BMC Cancer

Table 3 Association between ratios of omega-3 PUFAs and EC recurrence^a

Variable	Tertile1	Tertile2	Tertile3	P-trend^b
C20:5n3/C18:3n3	0.37(0.3–0.42)	0.59(0.53–0.65)	1.07(0.86–1.39)
Events/total(n/n)	4/65	4/66	5/64
Model 1	1.00	1.04(0.26–4.16)	1.21(0.32–4.58)	0.805
Model 2	1.00	0.82(0.2–3.36)	0.65(0.16–2.67)	0.541
Model 3	1.00	0.49(0.1–2.44)	0.5(0.11–2.24)	0.505
C22:5n3/C20:5n3	0.66(0.56–0.73)	1(0.92–1.07)	1.44(1.3–1.73)
Events/total(n/n)	6/65	3/66	2/64
Model 1	1.00	0.46(0.14–1.53)	0.13(0.02–1.03)	0.027
Model 2	1.00	0.96(0.26–3.6)	0.16(0.02–1.3)	0.074
Model 3	1.00	0.90(0.23–3.44)	0.14(0.02–1.17)	0.056

^aCox regression was used to estimate the HRs and CIs. PUFAs were classified into three groups based on the tertiles in total subjects, the lowest tertile group was treated as reference
^bP-trend values were conducted by assigning the median value to each tertile in the Cox regression models
Model 1: adjusting for age
Model 2: adjusting for age, BMI, and stage
Model 3: adjusting for age, BMI, stage, hormone therapy, and adjuvant therapy

ISSN: 1471-2407