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Table 2 Associations with lymph node status. The univariable analysis shows the associations between each RNA and lymph node status, while the multivariable analysis presents the associations after adjusting the effects of age, histology, and grade. All the analyses were carried out using linear mixed-effect models. The estimate and SE represent the estimated slope and its associated standard error of lymph node positive

From: Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models

 

Univariable analysis

Multivariable analysis

Estimate (SE)

t-value

p

Estimate (SE)

t-value

p

Total PR

0.297 (0.135)

2.205

0.028

0.315 (0.137)

2.305

0.022

PR-B

0.157 (0.108)

1.453

0.147

0.154 (0.110)

1.401

0.162

PR-A

0.553 (0.210)

2.626

0.009

0.639 (0.214)

2.994

0.003

ER

−0.116 (0.053)

−2.194

0.029

−0.082 (0.051)

−1.593

0.112

PR-A/PR-B

0.291 (0.231)

1.260

0.208

0.408 (0.234)

1.742

0.082