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Table 3 Correlation between platelets–lymphocyte ratio and clinicopathological features

From: Factors predictive of invasive ductal carcinoma in cases preoperatively diagnosed as ductal carcinoma in situ

Parameters

Platelets–lymphocyte ratio

p value

Low

(n = 74)

High

(n = 44)

Age at operation (years old)

  ≤ 60

51 (68.9%)

32 (72.7%)

 

  > 60

23 (31.1%)

12 (27.3%)

0.661

Symptoms

 Asymptomatic

29 (39.2%)

13 (29.5%)

 

 Symptomatic

45 (60.8%)

31 (70.5%)

0.290

Palpability

 Impalpabe

22 (29.7%)

11 (25.0%)

 

 Palpable

52 (70.3%)

33 (75.0%)

0.580

Tumor size (mm)

  ≤ 20.0

45 (60.8%)

26 (59.1%)

 

  > 20.0

29 (39.2%)

18 (40.9%)

0.854

Biopsy device

 Core needle biopsy

42 (56.8%)

25 (56.8%)

 

 Vacuum-assisted biopsy

32 (43.2%)

19 (43.2%)

0.995

Estrogen receptor

 Negative

15 (20.3%)

7 (15.9%)

 

 Positive

59 (79.7%)

37 (84.1%)

0.556

Progesterone receptor

 Negative

25 (33.8%)

12 (27.3%)

 

 Positive

49 (66.2%)

32 (72.7%)

0.461

HER2

  ≤ 2

63 (82.4%)

40 (90.9%)

 

 3

13 (17.6%)

4 (9.1%)

0.205

Ki67

  ≤ 14%

62 (83.8%)

36 (81.8%)

 

  > 14%

12 (16.2%)

8 (18.2%)

0.783

Grade of DCIS

 Low, intermediate

60 (81.1%)

38 (86.4%)

 

 High

14 (18.9%)

6 (13.6%)

0.460

Comedonecrosis

 Absence

36 (48.6%)

18 (40.9%)

 

 Presence

38 (51.4%)

26 (59.1%)

0.666

Intraductal calcification

 Absence

63 (85.1%)

36 (81.8%)

 

 Presence

11 (14.9%)

8 (18.2%)

0.635

Lymphoid infiltrate

 Negative, mild

49 (66.2%)

34 (77.3%)

 

 Moderate, severe

25 (33.8%)

10 (22.7%)

0.204

LDH

  ≤ ULN

67 (90.5%)

38 (86.4%)

 

  > ULN

7 (9.5%)

6 (13.6%)

0.484

CEA

  ≤ ULN

70 (94.6%)

41 (93.2%)

 

  > ULN

4 (5.4%)

3 (6.8%)

0.753

CA15–3

  ≤ ULN

71 (95.9%)

44 (100.0%)

 

  > ULN

3 (4.1%)

0 (0.0%)

0.176

Postoperative pathology

 DCIS only

50 (67.6%)

20 (45.5%)

 

 Invasive ductal carcinoma

24 (32.4%)

24 (54.5%)

0.018

  1. DCIS Ductal carcinoma in situ, HER2 Human epidermal growth factor receptor 2, LDH Lactate dehydrogenease, ULN Upper limit of normal. CEA Carcinoembryonic antigen