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Table 4 Logistic regression analysis for factors associated with inaccurate eGFR using MDRD

From: A novel nomogram to predict the reliability of estimated glomerular filtration rate formulae in oncology patients

 

Univariate analysis

Multivariate analysis

OR (95%CI)

P value

OR (95%CI)

P value

Age (years)

  < 50

1.00 (reference)

 

1.00 (reference)

 

 50–64

1.17 (0.72, 1.91)

0.519

1.41 (0.81, 2.45)

0.225

  ≥ 65

1.68 (0.99, 2.86)

0.055

2.56 (1.31, 4.98)

0.006

Sex, male

1.36 (0.90, 2.07)

0.143

1.36 (0.85, 2.17)

0.197

BMI (kg/m2)

  < 20

1.00 (reference)

 

1.00 (reference)

 

 20–24.9

0.95 (0.55, 1.66)

0.868

0.76 (0.42, 1.38)

0.37

 25–27.9

1.03 (0.55, 1.93)

0.916

0.78 (0.39, 1.57)

0.485

  ≥ 28

1.87 (0.83, 4.25)

0.133

1.34 (0.55, 3.27)

0.526

eGFR (ml/min)

  < 80

1.00 (reference)

 

1.00 (reference)

 

 80–89

1.62 (1.08, 2.43)

0.019

2.10 (1.29, 3.42)

0.003

  ≥ 120

6.70 (2.53, 17.74)

< 0.001

9.82 (3.47, 27.83)

< 0.001

BUN/Scr ratio

  < 20

1.00 (reference)

 

1.00 (reference)

 

  ≥ 20

1.68 (1.10, 2.57)

0.016

1.53 (0.96, 2.44)

0.076

Albumin (g/L)

  < 40

1.00 (reference)

 

1.00 (reference)

 

  ≥ 40

0.94 (0.63, 1.39)

0.750

1.16 (0.73,1.84)

0.519

Anemia

0.99 (0.64, 1.53)

0.962

1.09 (0.63, 1.88)

0.505

Diabetics

0.91 (0.47, 1.75)

0.769

0.83 (0.41, 1.69)

0.609

Hypertension

1.21 (0.80, 1.83)

0.364

1.06 (0.65, 1.73)

0.808

Obstructive nephropathy

0.93 (0.59, 1.46)

0.743

1.30 (0.77, 2.2)

0.323

  1. All variables listed in the table were included in the logistic regression model. OR odds ratio, 95% CIs 95% confidence intervals, BMI body mass index, eGFR estimated glomerular filtration rate, BUN blood urea nitrogen, Scr serum creatinine, BUN/Scr ratio blood urea nitrogen to creatinine ratio
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BMC Cancer

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