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Table 2 Screening accuracy for supplemental and primary US screening

From: Performance of ultrasonography screening for breast cancer: a systematic review and meta-analysis

Author, year Method Case Non-case Sensitivity
(95% CI)
Specificity
(95% CI)
+ +
Supplemental US screening studies
 Tagliafico, 2016 [21] Supplemental US 23 1 65 3142 0.96(0.77–1.00) 0.98(0.97–0.98)
 Kim, 2016 [22] Supplemental US 9 0 822 2340 1.00(0.63–1.00) 0.74(0.72–0.76)
 Weigert, 2015 [26] Supplemental US 24 15 411 9832 0.62(0.45–0.76) 0.96(0.96–0.96)
 Hwang, 2015 [25] Supplemental US 8 1 92 1626 0.89(0.51–0.99) 0.95(0.93–0.96)
 Moon, 2015 [24] Supplemental US 4 0 619 1382 1.00(0.40–1.00) 0.69(0.67–0.71)
 Parris, 2013 [28] Supplemental US 10 0 171 5338 1.00(0.66–1.00) 0.97(0.96–0.97)
 Girardi, 2013 [27] Supplemental US 41 0 381 21,709 1.00(0.89–1.00) 0.98(0.98–0.98)
 Leong, 2012 [32] Supplemental US 2 0 12 127 1.00(0.20–1.00) 0.91(0.85–0.95)
 Hooley, 2012 [31] Supplemental US 3 0 150 495 1.00(0.31–1.00) 0.77(0.73–0.80)
 Corsetti, 2011 [33] Supplemental US 32 8 363 6821 0.80(0.64–0.90) 0.95(0.94–0.95)
 Youk, 2011 [34] Supplemental US 10 1 41 394 0.91(0.57–1.00) 0.91(0.87–0.93)
 Brancato, 2007 [36] Supplemental US 2 0 106 5119 1.00(0.20–1.00) 0.98(0.98–0.98)
Joint screening studies
 Dong, 2017 [9] Primary MAM 84 15 604 31,215 0.85(0.76–0.91) 0.98(0.98–0.98)
  Primary US 61 38 389 31,430 0.62(0.51–0.71) 0.99(0.99–0.99)
 Ohuchi, 2016 [10] Primary MAM 117 85 2300 33,547 0.58(0.51–0.65) 0.94(0.93–0.94)
  Primary US 143 59 2289 33,558 0.71(0.64–0.77) 0.94(0.93–0.94)
 Berg, 2016 [11] Primary MAM 59 52 700 6662 0.53(0.43–0.63) 0.90(0.90–0.91)
  Primary US 58 53 1012 6350 0.52(0.43–0.62) 0.86(0.85–0.87)
 Shen, 2015 [23] Primary MAM 8 6 3 6913 0.57(0.30–0.81) 1.00(1.00–1.00)
  Primary US 14 0 6 6910 1.00(0.73–1.00) 1.00(1.00–1.00)
 Brem, 2015 [39] Primary MAM 82 30 2219 12,987 0.73(0.64–0.81) 0.85(0.85–0.86)
  Primary US 95 17 2656 12,550 0.85(0.77–0.91) 0.83(0.82–0.83)
 Huang, 2012 [30] Primary MAM 28 5 48 2947 0.85(0.67–0.94) 0.98(0.98–0.99)
  Primary US 24 9 19 2976 0.73(0.54–0.86) 0.99(0.99–1.00)
 Kelly, 2010 [40] Primary MAM 23 34 36 4326 0.40(0.28–0.54) 0.99(0.99–0.99)
  Primary US 38 19 61 4301 0.67(0.53–0.78) 0.99(0.98–0.99)
 Wilczek, 2016 [38] Primary MAM 7 4 16 1641 0.64(0.32–0.88) 0.99(0.98–0.99)
  Primary US 11 0 27 1630 1.00(0.68–1.00) 0.98(0.98–0.99)
 Venturini, 2013 [29] Primary MAM 12 2 99 1553 0.86(0.56–0.97) 0.94(0.93–0.95)
  Primary US 2 12 8 813 0.14(0.03–0.44) 0.99(0.98–1.00)
 Weinstein, 2009 [35] Primary MAM 7 13 37 512 0.35(0.16–0.59) 0.93(0.91–0.95)
  Primary US 3 17 36 511 0.15(0.04–0.39) 0.93(0.91–0.95)
 Honjo, 2007 [37] Primary MAM 8 5 271 3259 0.62(0.32–0.85) 0.92(0.91–0.93)
  Primary US 7 6 158 3372 0.54(0.26–0.80) 0.96(0.95–0.96)
  1. CI Confidential interval; MAM Mammography; US Ultrasonography