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Table 2 Screening accuracy for supplemental and primary US screening

From: Performance of ultrasonography screening for breast cancer: a systematic review and meta-analysis

Author, year

Method

Case

Non-case

Sensitivity

(95% CI)

Specificity

(95% CI)

+

+

Supplemental US screening studies

 Tagliafico, 2016 [21]

Supplemental US

23

1

65

3142

0.96(0.77–1.00)

0.98(0.97–0.98)

 Kim, 2016 [22]

Supplemental US

9

0

822

2340

1.00(0.63–1.00)

0.74(0.72–0.76)

 Weigert, 2015 [26]

Supplemental US

24

15

411

9832

0.62(0.45–0.76)

0.96(0.96–0.96)

 Hwang, 2015 [25]

Supplemental US

8

1

92

1626

0.89(0.51–0.99)

0.95(0.93–0.96)

 Moon, 2015 [24]

Supplemental US

4

0

619

1382

1.00(0.40–1.00)

0.69(0.67–0.71)

 Parris, 2013 [28]

Supplemental US

10

0

171

5338

1.00(0.66–1.00)

0.97(0.96–0.97)

 Girardi, 2013 [27]

Supplemental US

41

0

381

21,709

1.00(0.89–1.00)

0.98(0.98–0.98)

 Leong, 2012 [32]

Supplemental US

2

0

12

127

1.00(0.20–1.00)

0.91(0.85–0.95)

 Hooley, 2012 [31]

Supplemental US

3

0

150

495

1.00(0.31–1.00)

0.77(0.73–0.80)

 Corsetti, 2011 [33]

Supplemental US

32

8

363

6821

0.80(0.64–0.90)

0.95(0.94–0.95)

 Youk, 2011 [34]

Supplemental US

10

1

41

394

0.91(0.57–1.00)

0.91(0.87–0.93)

 Brancato, 2007 [36]

Supplemental US

2

0

106

5119

1.00(0.20–1.00)

0.98(0.98–0.98)

Joint screening studies

 Dong, 2017 [9]

Primary MAM

84

15

604

31,215

0.85(0.76–0.91)

0.98(0.98–0.98)

 

Primary US

61

38

389

31,430

0.62(0.51–0.71)

0.99(0.99–0.99)

 Ohuchi, 2016 [10]

Primary MAM

117

85

2300

33,547

0.58(0.51–0.65)

0.94(0.93–0.94)

 

Primary US

143

59

2289

33,558

0.71(0.64–0.77)

0.94(0.93–0.94)

 Berg, 2016 [11]

Primary MAM

59

52

700

6662

0.53(0.43–0.63)

0.90(0.90–0.91)

 

Primary US

58

53

1012

6350

0.52(0.43–0.62)

0.86(0.85–0.87)

 Shen, 2015 [23]

Primary MAM

8

6

3

6913

0.57(0.30–0.81)

1.00(1.00–1.00)

 

Primary US

14

0

6

6910

1.00(0.73–1.00)

1.00(1.00–1.00)

 Brem, 2015 [39]

Primary MAM

82

30

2219

12,987

0.73(0.64–0.81)

0.85(0.85–0.86)

 

Primary US

95

17

2656

12,550

0.85(0.77–0.91)

0.83(0.82–0.83)

 Huang, 2012 [30]

Primary MAM

28

5

48

2947

0.85(0.67–0.94)

0.98(0.98–0.99)

 

Primary US

24

9

19

2976

0.73(0.54–0.86)

0.99(0.99–1.00)

 Kelly, 2010 [40]

Primary MAM

23

34

36

4326

0.40(0.28–0.54)

0.99(0.99–0.99)

 

Primary US

38

19

61

4301

0.67(0.53–0.78)

0.99(0.98–0.99)

 Wilczek, 2016 [38]

Primary MAM

7

4

16

1641

0.64(0.32–0.88)

0.99(0.98–0.99)

 

Primary US

11

0

27

1630

1.00(0.68–1.00)

0.98(0.98–0.99)

 Venturini, 2013 [29]

Primary MAM

12

2

99

1553

0.86(0.56–0.97)

0.94(0.93–0.95)

 

Primary US

2

12

8

813

0.14(0.03–0.44)

0.99(0.98–1.00)

 Weinstein, 2009 [35]

Primary MAM

7

13

37

512

0.35(0.16–0.59)

0.93(0.91–0.95)

 

Primary US

3

17

36

511

0.15(0.04–0.39)

0.93(0.91–0.95)

 Honjo, 2007 [37]

Primary MAM

8

5

271

3259

0.62(0.32–0.85)

0.92(0.91–0.93)

 

Primary US

7

6

158

3372

0.54(0.26–0.80)

0.96(0.95–0.96)

  1. CI Confidential interval; MAM Mammography; US Ultrasonography