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Fig. 4 | BMC Cancer

Fig. 4

From: Multi-nanolayer drug delivery using radiofrequency plasma technology

Fig. 4

In vivo: films are applicable to the BALB/c mouse animal model. a. Implanted film in the BALB/c mouse model where the tumor was produced in the inguinal lymph node (white arrow indicates the film position). b. Sampling of the control film after implantation. c. Sampling of the treated film after implantation. d. 1- Pt detection via ICP-MS in nontreated (NT) and treated (T) mice. 2- Histogram of the NT and T groups, P < 0.0286. e. 1- Rate of decreasing volume in the treated group, T, compared with the control, NT. 2- Histogram of the NT and T groups, P < 0.0047. f. Film surface from the contact zone with the nodule was checked; SEM showed a difference in the adherence density in the presence (zone 1) or absence (zone 2) of platinum. g. Zone 1 checked for Pt presence (purple peak). h. Zone 2, where no Pt was detected. Yellow plus signs indicate to the checked area with EDX. Au in the graphs is for gold, N is for nitrogen, C is for carbon, O is for oxygen, Na is for sodium. Y-axis (cps/eV) is counts per second per eV. X-axis (KeV) is kilo electron volts

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