CT-based radiomics scores predict response to neoadjuvant chemotherapy and survival in patients with gastric cancer

Table 1 Clinicopathological characteristics of the training and validation cohorts

Factors	Training cohort (n = 74)	Validation cohort (n = 32)	P value
Age (years, mean ± SD)	55.15 ± 11.43	54.13 ± 12.68	0.68
Gender			0.53
Male	48	18
Female	26	14
BMI (kg/m²)	21 ± 3	22 ± 3	0.12
Preoperative T stage			0.39
2	1	0
3	11	2
4	62	29
Preoperative N status			0.99
0	2	1
1–3	72	31
Preoperative M status			0.85
0	47	19
1	27	13
Postoperative T stage			0.83
1–2	11	6
3–4	63	26
Postoperative N status			0.06
0	35	8
1–3	39	24
Postoperative M status			0.90
0	53	24
1	21	8
Postoperative TNM stage			0.23
0	3	3
1	6	1
2	22	5
3	22	15
4	21	8
AFP (ng/mL)	9.25 ± 17.79	6.48 ± 8.33	0.40
CEA (IU/L)			0.23
Normal	50	26
Elevated	24	6
CA125 (IU/L)			0.08
Normal	73	29
Elevated	1	3
CA199 (IU/L)			1.00
Normal	64	27
Elevated	10	5
Operative duration (min)	349.46 ± 116.47	359.22 ± 111.98	0.69
Blood transfusion (ml)	347.92 ± 506.39	362.50 ± 458.43	0.89
Total number of dissected lymph node	40.81 ± 18.67	44.09 ± 17.77	0.40
Number of positive lymph node	5.27 ± 9.01	7.34 ± 10.42	0.30
Treatment response			0.25
TRG 1	3	3
TRG 2	34	14
TRG 3	24	10
TRG 4	10	4
TRG 5	3	1

Abbreviations: BMI body mass index, PS performance status, AFP alpha-fetoprotein, CEA carcinoembryonic antigen, TRG tumor regression grading

ISSN: 1471-2407