Table 4 Prognostic factors for overall survival with ovarian cancer selected by Cox’s uni- and multivariate analysis
From: Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ovarian cancer
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Hazard ratio (95%CI) | p | Hazard ratio (95%CI) | p | |
Age (≥55) | 1.094 (0.270–4.441) | 0.900 | ||
FIGO stage (III-IV) | 7.256 (0.913–57.650) | 0.061 | ||
Histopathologic type (High-grade serous carcinoma) | 1.487 (0.423–5.223) | 0.536 | ||
Completeness of surgical reduction (Suboptimal) | 4.691 (1.346–16.343) | 0.015* | 3.610 (1.020–12.779) | 0.047* |
Treatment response (non-responders) | 11.701 (2.291–59.775) | 0.003* | ||
Tumor progression (platinum-resistant) | 12.210 (2.583–57.716) | 0.002* | ||
CA125 (≥461.35) | 2.272 (0.651–7.925) | 0.198 | ||
Drp1 (≥10.5) | 3.847 (0.479–30.881) | 0.205 | ||
phospho-Drp1Ser637 (≥7.0) | 2.797 (0.787–9.942) | 0.112 | ||
CaMKI (≥10.5) | 4.877 (1.011–23.519) | 0.048* | 3.844 (0.772–19.145) | 0.100 |