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Table 2 Changes in TILs and CD8+ T cells following NAC

From: Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer

 

Pre-NAC cohort (n = 6)

Post-NAC cohort (n = 17)

Percentage of TILs

 Stromal TILs

29.8% (1–80%)

24.9% (2–70%)

Percentage of CD8+ T cells

 Overall CD8+ T cells

18.3% (0.5–60%)

15.7% (1–50%)

 Stromal CD8+ T cells

24.6% (1–70%)

21.2% (1–60%)

 Intratumoral CD8+ T cells

12.0% (0–50%)

7.9% (0–40%)

  1. Values are denoted as means with ranges in the parentheses