Table 3 Univariate analysis of prognostic factors
Prognostic factor | n | Median OS (months) | p value |
|---|---|---|---|
Sex | |||
 Male | 75 | 6.5 | 0.052 |
 Female | 29 | 10.6 |  |
ECOG PS | |||
 0 | 93 | 7.3 | 0.038 |
 1, 2 | 11 | 5.2 |  |
Age | |||
  ≥ 70 | 12 | 7 | 0.334 |
  < 70 | 92 | 7.3 |  |
Pancreatic resection | |||
 Yes | 31 | 7 | 0.319 |
 No | 73 | 8 |  |
First-line therapy duration | |||
  ≤ 4 months | 19 | 7 | 0.459 |
  > 4 months | 85 | 7.3 |  |
Liver metastasis | |||
 Yes | 72 | 6.5 | 0.054 |
 No | 32 | 9.9 |  |
CEA (ng/mL) | |||
  ≤ 10 | 69 | 9.9 | < 0.001 |
  > 10 | 35 | 6.2 |  |
CA19–9 (IU/mL) | |||
  ≤ 1000 | 57 | 7.5 | 0.621 |
  > 1000 | 47 | 7 |  |
Alb (g/dL) | |||
  < 3.5 | 40 | 6 | 0.014 |
  ≥ 3.5 | 64 | 9.4 |  |
CRP (mg/dL) | |||
  ≤ 0.16 | 35 | 11.6 | < 0.001 |
  > 0.16 | 69 | 5.9 |  |
GPS | |||
 Low (0) | 44 | 10.6 | < 0.001 |
 High (1, 2) | 60 | 6 |  |
NLR | |||
  ≤ 5.0 | 96 | 8.7 | < 0.001 |
  > 5.0 | 8 | 4.6 |  |