Table 3 The value of SCC antigen levels on assessment of rate of positive lymph nodes and survival time of patients with cervical squamous cell carcinoma
Group | Factors | Cut-off | Sen (%) | Spe (%) | PPV (%) | NPV (%) | AUC (95%CI) | P of AUC |
|---|---|---|---|---|---|---|---|---|
Positive rate of lymph nodes | ||||||||
 Conventional group (n = 39) | SCC antigen | ≥ 6.75 | 80.0 (16/20) | 100.0 (19/19) | 100.0 (16/16) | 82.6 (19/23) | 0.893 (0.780, 1.000) | < 0.001 |
 NACT group (n = 64) | ISCC | ≥ 3.90 | 80.8 (21/26) | 47.4 (18/38) | 51.2 (21/41) | 78.3 (18/23) | 0.677 (0.543, 0.810) | 0.017 |
SSCC | ≥ 2.10 | 73.1 (19/26) | 71.1 (27/38) | 63.3 (19/30) | 79.4 (27/34) | 0.739 (0.610, 0.869) | 0.001 | |
FSCC | ≥ 1.45 | 80.8 (21/26) | 50.0 (19/38) | 52.5 (21/40) | 79.2 (19/24) | 0.634 (0.495, 0.773) | 0.071 | |
TSCC | ≥ 1.55 | 76.9 (20/26) | 57.9 (22/38) | 55.6 (20/36) | 78.6 (22/28) | 0.655 (0.519, 0.791) | 0.036 | |
Survival times | ||||||||
 Conventional group (n = 39) | SCC | ≤ 3.45 | 80.0 (4/5) | 67.6 (23/34) | 26.7 (4/15) | 95.8 (23/24) | 0.656 (0.359, 0.953) | 0.266 |
 NACT group (n = 63) | ISCC | ≥ 4.55 | 100.0 (11/11) | 57.7 (30/52) | 33.3 (11/33) | 100.0 (30/30) | 0.798 (0.679, 0.917) | 0.002 |
SSCC | ≥ 2.70 | 81.8 (9/11) | 71.2 (37/52) | 37.5 (9/24) | 94.9 (37/39) | 0.803 (0.667, 0.940) | 0.002 | |
OSCC | ≥ 2.75 | 81.8 (9/11) | 80.8 (42/52) | 47.4 (9/19) | 95.5 (42/44) | 0.839 (0.730, 0.948) | < 0.001 | |
FSCC | ≥ 2.80 | 81.8 (9/11) | 61.5 (32/52) | 31.0 (9/29) | 94.1 (32/34) | 0.738 (0.585, 0.891) | 0.014 | |
TSCC | ≥ 1.35 | 90.9 (10/11) | 46.2 (24/52) | 26.3 (10/38) | 96.0 (24/25) | 0.677 (0.507, 0.846) | 0.067 | |