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Table 4 Cox regression for PFS and OS

From: Prognostic model based on the geriatric nutritional risk index and sarcopenia in patients with diffuse large B-cell lymphoma

 PFSOS
UnivariateMultivariateUnivariateMultivariate
HR95% CIPHR95% CIPHR95% CIPHR95% CIP
GNRI/sarcopenia risk
 Low cachexia riskRef.  Ref.  Ref.  Ref.  
 High cachexia risk4.3082.915–6.367<  0.0012.7731.826–4.212<  0.0014.9613.302–7.452<  0.0013.3482.169–5.167<  0.001
BMI (<  23 kg/m2vs. ≥ 23 kg/m2)1.0160.691–1.4940.935   1.0960.735–1.6320.653   
NCCN-IPI
 Low to Low-intermediateRef.  Ref.  Ref.  Ref.  
 High-intermediate to High5.9593.649–9.732<  0.0014.3422.580–7.308<  0.0016.4743.855–10.874<  0.0014.7932.770–8.292<  0.001
Other clinical variables
 Sex (male vs. female)1.1210.757–1.6590.569   1.1090.739–1.6640.619   
 B-symptoms (present vs. absent)2.5741.694–3.913<  0.0011.3050.839–2.0310.2372.3721.533–3.671<  0.0011.1730.742–1.8560.494
 Bulky disease (bulky vs. non-bulky)0.8740.513–1.4900.621   0.8100.459–1.4280.466   
  1. Abbreviations: PFS progression-free survival, OS overall survival, HR hazard ratio, CI confidence interval, GNRI Geriatric Nutritional Risk Index, BMI body mass index, NCCN-IPI National Comprehensive Cancer Network-International Prognostic Index