Table 2 Patients with different SEER stages
From: Clinical characteristics and prognostic factors of Hurthle cell carcinoma: a population based study
Characteristics | Local disease (n = 1740) | Regional disease (n = 245) | Distant disease (n = 89) | P-value | Pa-value | Pb-value | Pc-value |
|---|---|---|---|---|---|---|---|
Age (year) | 54 ± 14.8 | 61 ± 17.1 | 69 ± 13.5 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Gender, n (%) | 0.001 | 0.010 | 0.370 | 0.005 | |||
Male | 476 (27.4) | 87 (35.5) | 37 (41.6) | ||||
Female | 1264 (72.6) | 158 (64.5) | 52 (58.4) | ||||
Race, n (%) | 0.016 | 0.003 | 0.064 | 0.898 | |||
White | 1435 (82.5) | 206 (84.1) | 72 (82.6) | ||||
Black | 168 (9.7) | 9 (3.7) | 10 (11.2) | ||||
American Indian/Alaska Native, Asian/Pacific Islander | 111 (6.4) | 25 (10.2) | 7 (7.9) | ||||
Unknown | 26 (1.5) | 5 (2.0) | 0 | ||||
Tumor multifocality, n (%) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||
No | 1428 (82.1) | 173 (70.6) | 51 (57.3) | ||||
Yes | 268 (15.4) | 58 (23.7) | 25 (28.1) | ||||
Unspecified | 44 (2.5) | 14 (5.7) | 13 (14.6) | ||||
Tumor extension, n (%) | < 0.001 | < 0.001 | 0.023 | < 0.001 | |||
Intrathyroidal | 1700 (97.7) | 49 (20.0) | 19 (21.3) | ||||
Extrathyroidal | 40 (2.3) | 195 (79.6) | 66 (74.2) | ||||
Unspecified | 0 | 1 (0.4) | 4 (4.5) | ||||
T-stage, n (%) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||
T1 | 467 (26.8) | 16 (6.5) | 3 (3.4) | ||||
T2 | 678 (39.0) | 21 (8.6) | 8 (9.0) | ||||
T3 | 526 (30.2) | 164 (66.9) | 18 (20.2) | ||||
T4 | 1 (0.1) | 42 (17.1) | 54 (60.7) | ||||
Unspecified | 68 (3.9) | 2 (0.8) | 6 (6.7) | ||||
N-stage, n (%) | < 0.001 | < 0.001 | 0.023 | < 0.001 | |||
N0 | 1703 (97.9) | 153 (62.4) | 52 (58.4) | ||||
N1 | 0 | 85 (34.7) | 28 (31.5) | ||||
Unspecified | 37 (2.1) | 7 (2.9) | 9 (10.1) | ||||
M-stage, n (%) | < 0.001 | 0.167 | < 0.001 | < 0.001 | |||
M0 | 1718 (98.7) | 240 (98.0) | 30 (33.7) | ||||
M1 | 0 | 0 | 59 (66.3) | ||||
Unspecified | 22 (1.3) | 5 (2.0) | 0 |